Department of Pediatrics, Lin-Shin Hospital, Taichung, Taiwan.
Pediatr Neonatol. 2011 Feb;52(1):3-4. doi: 10.1016/j.pedneo.2010.12.012. Epub 2011 Feb 18.
Traditional treatment of muscular ventricular septal defect (VSD) is surgical closure, but it carries considerable morbidity and mortality. The Amplatzer muscular VSD occluder (AGA Medical Corporation, Plymouth, MN, USA) was approved by the United States Food and Drug Administration in September 2007 and by the Taiwan Department of Health in September 2009. It is a self-expandable double-disc device made from a nitinol wire mesh. Dacron polyester patches are sewn into each disc and the connecting waist to increase the thrombogenicity of the device. Many reports have shown that transcatheter device closure of muscular VSDs is effective and safe. It has no scar, less pain, shorter hospital stay, and less cost compared to the traditional open heart surgery.
传统的肌部室间隔缺损(VSD)治疗方法是手术闭合,但它具有相当高的发病率和死亡率。Amplatzer 肌部 VSD 封堵器(AGA Medical Corporation,明尼苏达州普利茅斯)于 2007 年 9 月获得美国食品和药物管理局批准,于 2009 年 9 月获得台湾卫生署批准。它是一种由镍钛诺金属丝编织而成的自膨胀双盘装置。每个盘片和连接腰部都缝有涤纶聚酯补片,以增加装置的血栓形成性。许多报告表明,经导管装置闭合肌部 VSD 是有效和安全的。与传统的心脏直视手术相比,它没有疤痕,疼痛更少,住院时间更短,成本更低。