多囊卵巢综合征患者腹腔镜卵巢烧灼术后生物活性黄体生成素的变化。
Changes of bioactive luteinizing hormone after laparoscopic ovarian cautery in patients with polycystic ovarian syndrome.
作者信息
Sakata M, Tasaka K, Kurachi H, Terakawa N, Miyake A, Tanizawa O
机构信息
Department of Obstetrics and Gynecology, Osaka University Medical School, Japan.
出版信息
Fertil Steril. 1990 Apr;53(4):610-3. doi: 10.1016/s0015-0282(16)53451-7.
The serum levels of bioactive luteinizing hormone (LH), immunoreactive LH, follicle-stimulating hormone, androstenedione (A), and testosterone (T) were determined in nine anovulatory women with polycystic ovarian syndrome (PCOS) before and after laparoscopic ovarian cautery. Eight ovulated spontaneously and three conceived after treatment. Before treatment, the mean (+/- SEM) levels of bioactive LH, immunoreactive LH, A, and T were 51.4 +/- 8.6 mIU/mL, 36.0 +/- 4.5 mIU/mL, 1.98 +/- 0.35 ng/mL, and 1.18 +/- 0.13 ng/mL, respectively, which were significantly higher than those of five control women (19.2 +/- 1.6 mIU/mL, 21.4 +/- 1.2 mIU/mL, 0.54 +/- 0.03 ng/mL, 0.28 +/- 0.03 ng/mL). After treatment, the mean levels of these hormones had significantly decreased. Decreases in the levels of these hormones by laparoscopic ovarian cautery in women with PCOS may result in both restoration of the ovulatory cycle and achievement of pregnancy.
在9名患有多囊卵巢综合征（PCOS）的无排卵女性中，测定了腹腔镜卵巢烧灼术前和术后生物活性促黄体生成素（LH）、免疫反应性LH、促卵泡激素、雄烯二酮（A）和睾酮（T）的血清水平。8名女性治疗后自发排卵，3名女性受孕。治疗前，生物活性LH、免疫反应性LH、A和T的平均（±标准误）水平分别为51.4±8.6 mIU/mL、36.0±4.5 mIU/mL、1.98±0.35 ng/mL和1.18±0.13 ng/mL，显著高于5名对照女性（19.2±1.6 mIU/mL、21.4±1.2 mIU/mL、0.54±0.03 ng/mL、0.28±0.03 ng/mL）。治疗后，这些激素的平均水平显著下降。腹腔镜卵巢烧灼术使PCOS女性体内这些激素水平降低，可能会恢复排卵周期并实现妊娠。
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