Gonda Tamas A, Saif Muhammad Wasif
Division of Digestive and Liver Disease, Columbia University Medical Center, New York, NY, USA.
JOP. 2011 Mar 9;12(2):83-5.
Pancreatic cancer presents at an advanced stage in majority of the patients, hence resulting in a very dismal prognosis. Novel and effective methods to detect and screen pancreatic cancer and its precursors are warranted. The U.S. Multi-Society Task Force recommends against routine screening for pancreatic cancer in asymptomatic adults using abdominal palpation, ultrasonography, or serologic markers. Moreover, the screening for persons with hereditary predisposition to develop pancreatic cancer has not been validated. Herein, the authors summarize the data presented at the 2011 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium in detecting early stage pancreatic cancer (Abstracts #187 and #193).
大多数胰腺癌患者就诊时已处于晚期，因此预后非常糟糕。有必要采用新颖且有效的方法来检测和筛查胰腺癌及其癌前病变。美国多学会特别工作组不建议对无症状成年人使用腹部触诊、超声检查或血清学标志物进行胰腺癌的常规筛查。此外，对有胰腺癌遗传易感性人群的筛查尚未得到验证。在此，作者总结了在2011年美国临床肿瘤学会（ASCO）胃肠道癌症研讨会上发表的关于检测早期胰腺癌的数据（摘要#187和#193）。
