Tondeur Marianne, Hambye Anne-Sophie, Sand Alain, Ham Hamphrey
Service des Radio-Isotopes, CHU Saint-Pierre, Brussels, Belgium.
Nucl Med Commun. 2011 May;32(5):410-5. doi: 10.1097/MNM.0b013e32834508ee.
In nuclear medicine, reproducibility studies allow the assessment of the robustness of a technique. They could also be used in continuing education. This study evaluates this educational impact.
Two series of clinical data and I-123 fluoropropyl-carbomethoxy-iodophenyl-nortropane single photon emission tomography images from 12 patients were prepared before initiating the study. Each series covered similarly a wide spectrum of clinical situations and images. Nuclear medicine physicians having experience with I-123 fluoropropyl-carbomethoxy-iodophenyl-nortropane single photon emission tomography were recruited and assigned two similar groups regarding their level of experience and type of institutions from which they were issued. Clinical data and images were transmitted by e-mail. For each case, observers had to choose among three answers: normal, equivocal, and abnormal. Answers were returned anonymously. Before the second series was sent, observers from group A had a collegiate discussion on the results of the first series of cases. Observers from group B received the second series without any information regarding analysis of series 1.
In group A, median agreement increased from 75% (series 1) to 100% (series 2); in group B it was 75% (series 1) and 87% (series 2). In group A, a 100% agreement was observed for four cases (series 1) and for eight cases (series 2). In group B, a 100% agreement was observed for four cases for both series.
These preliminary results, obtained in a small sample of observers, suggest that participating and discussing results of interobserver reproducibility studies seems to have a positive educational impact and therefore improves interobserver reproducibility.
在核医学中,重复性研究可用于评估技术的稳健性。它们也可用于继续教育。本研究评估这种教育影响。
在研究开始前,准备了来自12名患者的两组临床数据和I-123氟丙基-碳甲氧基-碘苯基-去甲托烷单光子发射断层扫描图像。每组均涵盖了广泛的临床情况和图像。招募了有I-123氟丙基-碳甲氧基-碘苯基-去甲托烷单光子发射断层扫描经验的核医学医师,并根据他们的经验水平和所在机构类型分为两个相似的组。临床数据和图像通过电子邮件发送。对于每个病例,观察者必须从三个答案中选择:正常、可疑和异常。答案匿名返回。在发送第二组之前,A组的观察者对第一组病例的结果进行了集体讨论。B组的观察者收到第二组时没有关于第一组分析的任何信息。
A组的中位一致性从75%(第一组)提高到100%(第二组);B组为75%(第一组)和87%(第二组)。A组中,第一组有4例(第二组有8例)观察到100%的一致性。B组中,两组均有4例观察到100%的一致性。
在一小部分观察者中获得的这些初步结果表明,参与并讨论观察者间重复性研究的结果似乎具有积极的教育影响,因此提高了观察者间的重复性。