Nurse P
Department of Biochemistry, University of Oxford, UK.
Nature. 1990 Apr 5;344(6266):503-8. doi: 10.1038/344503a0.
The onset of M-phase is regulated by a mechanism common to all eukaryotic cells. Entry into M-phase is determined by activation of the p34cdc2 protein kinase which requires p34cdc2 dephosphorylation and association with cyclin.
M期的起始由所有真核细胞共有的一种机制调控。进入M期由p34cdc2蛋白激酶的激活所决定,这需要p34cdc2去磷酸化并与细胞周期蛋白结合。