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Highly enantioselective synthesis of designed chiral acyclonucleosides and acyclonucleotides by organocatalytic aza-Michael addition.

作者信息

Guo Hai-Ming, Yuan Teng-Fei, Niu Hong-Ying, Liu Jin-Ying, Mao Run-Ze, Li De-Yang, Qu Gui-Rong

机构信息

College of Chemistry and Environmental Science, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, 46 Jianshe Road, Xinxiang, 453007, PR China.

出版信息

Chemistry. 2011 Apr 4;17(15):4095-8. doi: 10.1002/chem.201100435. Epub 2011 Mar 8.

DOI:10.1002/chem.201100435
PMID:21387438
Abstract
摘要

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Bifunctional cinchona alkaloid-squaramide-catalyzed highly enantioselective aza-Michael addition of indolines to α,β-unsaturated ketones.双功能金鸡纳生物碱-方酰胺催化二氢吲哚对α,β-不饱和酮的高对映选择性氮杂-Michael加成反应。
Tetrahedron Lett. 2013 Jul 3;54(27):3500-3502. doi: 10.1016/j.tetlet.2013.04.080.