Raymond J M, Collet D, Arnoux R, Dumas F, Couzigou P, Perissat J, Amouretti M
Département d'Hépato-Gastro-Entérologie, Hôpital du Haut-Levêque, Pessac.
Presse Med. 1990 Mar 10;19(9):407-9.
We report the results of extracorporeal piezoelectric lithotripsy of gallbladder stones, using the EDAP LT 01 device, in 60 patients treated without anaesthesia or analgesia. Fragmentation was satisfactory (i.e. with fragments less than 5 mm wide) in 31 patients (52 per cent) after multiple sessions (mean: 1.6). The satisfactory fragmentation rate was higher in patients with stones smaller than 20 mm (63 vs 8 per cent; P less than 0.01) and not different in patients with solitary or multiple stones (53 vs 50 per cent). After bile acid dissolution treatment during 3, 6 and 12 months, the stone-free rates were 23, 41 and 64 per cent respectively, and significantly better at 3 and 6 months in patients with satisfactory fragmentation (42 vs 4 per cent; P less than 0.05, and 71 vs 9 per cent; P less than 0.01). Fourteen patients (23 per cent) reported biliary colic, but only one required cholecystectomy. No severe complication was observed. Piezoelectric lithotripsy is safe, requires short hospitalization and gives interesting results when the stones are less than 20 mm wide.
我们报告了使用EDAP LT 01设备对60例未进行麻醉或镇痛治疗的胆囊结石患者进行体外压电碎石术的结果。经过多次治疗(平均1.6次)后,31例患者(52%)的结石破碎情况令人满意(即碎片宽度小于5毫米)。结石小于20毫米的患者中,令人满意的破碎率更高(63%对8%;P小于0.01),单发或多发结石患者的破碎率无差异(53%对50%)。在进行3个月、6个月和12个月的胆汁酸溶解治疗后,无结石率分别为23%、41%和64%,结石破碎情况令人满意的患者在3个月和6个月时的无结石率明显更高(42%对4%;P小于0.05,71%对9%;P小于0.01)。14例患者(23%)报告有胆绞痛,但只有1例需要进行胆囊切除术。未观察到严重并发症。当结石宽度小于20毫米时,压电碎石术是安全的,住院时间短,且能取得不错的效果。