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[仅表现为呼吸道症状的复发性多软骨炎一例]

[A case of relapsing polychondritis with respiratory symptom manifestation alone].

作者信息

Kanazawa Yuji, Kikuchi Masahiro, Naito Yasushi, Shinohara Shogo, Fujiwara Keizo, Tona Yosuke, Yamazaki Hiroshi, Kurihara Risa

机构信息

Department of Otolaryngology/Head and Neck Surgery, Kobe City Medical Center General Hospital, Kobe.

出版信息

Nihon Jibiinkoka Gakkai Kaiho. 2011 Jan;114(1):30-3. doi: 10.3950/jibiinkoka.114.30.

Abstract

Relapsing polychondritis, a comparatively rare condition systemically affecting organs containing collagen, such as cartilage tissue, is diagnosed based on clinical manifestations and pathological findings. Our case report involves a respiratory symptom alone. A 65-year-old man seen for fever and dyspnea was found in computed tomography and endoscopy to have subglottic and tracheal stenosis, necessitating tracheostomy and tracheal cartilage biopsy. Pathologically bony cartilage change was seen but no definite auricular inflammation findings. Additional auricular cartilage biopsy, showed no inflammation. Residual auricular cartilage scarring, however, indicated cartilage destruction by previous inflammation or trauma, yielding a final diagnosis of relapsing polychondritis. Steroid therapy quickly relieved symptoms. Auricular cartilage biopsy thus proved useful in definitively diagnosing this condition.

摘要

复发性多软骨炎是一种相对罕见的疾病,会系统性地影响含有胶原蛋白的器官,如软骨组织,其诊断基于临床表现和病理检查结果。我们的病例报告仅涉及呼吸系统症状。一名因发热和呼吸困难前来就诊的65岁男性,在计算机断层扫描和内窥镜检查中发现声门下和气管狭窄,需要进行气管切开术和气管软骨活检。病理检查可见骨软骨改变,但未发现明确的耳廓炎症表现。额外的耳廓软骨活检也未发现炎症。然而,残留的耳廓软骨瘢痕表明先前存在炎症或创伤导致软骨破坏,最终诊断为复发性多软骨炎。类固醇治疗迅速缓解了症状。因此,耳廓软骨活检被证明对明确诊断这种疾病很有用。

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