Zilembo Nicoletta, Vitali Milena, Pietrantonio Filippo, Platania Marco, Del Vecchio Michele, Bajetta Emilio
Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Tumori. 2010 Nov-Dec;96(6):1031-4.
Malignant pleural mesothelioma is a neoplasm characterized by an increasing incidence and poor prognosis. When surgical treatment cannot be performed, systemic chemotherapy remains the main therapeutic option. Here we report the case of a 41-year-old female patient with epithelioid malignant pleural mesothelioma who was treated with carboplatin and pemetrexed despite her critical condition. She showed an impressive response to this first-line chemotherapy and, after disease progression, to further chemotherapy with gemcitabine and vinorelbine. She is still alive, with unexpectedly long-lasting survival.
恶性胸膜间皮瘤是一种发病率不断上升且预后较差的肿瘤。当无法进行手术治疗时，全身化疗仍是主要的治疗选择。在此，我们报告一例41岁上皮样恶性胸膜间皮瘤女性患者的病例，尽管病情危急，但她接受了卡铂和培美曲塞治疗。她对一线化疗表现出显著反应，疾病进展后，又接受了吉西他滨和长春瑞滨的进一步化疗。她仍然存活，生存期出人意料地长。
