一例具有显著临床反应和长期生存的罕见大型胸膜间皮瘤：病例报告及文献综述
An unusually large pleural mesothelioma with an outstanding clinical response and long lasting survival: a case report and literature review.
作者信息
Zilembo Nicoletta, Vitali Milena, Pietrantonio Filippo, Platania Marco, Del Vecchio Michele, Bajetta Emilio
机构信息
Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
出版信息
Tumori. 2010 Nov-Dec;96(6):1031-4.
Malignant pleural mesothelioma is a neoplasm characterized by an increasing incidence and poor prognosis. When surgical treatment cannot be performed, systemic chemotherapy remains the main therapeutic option. Here we report the case of a 41-year-old female patient with epithelioid malignant pleural mesothelioma who was treated with carboplatin and pemetrexed despite her critical condition. She showed an impressive response to this first-line chemotherapy and, after disease progression, to further chemotherapy with gemcitabine and vinorelbine. She is still alive, with unexpectedly long-lasting survival.
恶性胸膜间皮瘤是一种发病率不断上升且预后较差的肿瘤。当无法进行手术治疗时，全身化疗仍是主要的治疗选择。在此，我们报告一例41岁上皮样恶性胸膜间皮瘤女性患者的病例，尽管病情危急，但她接受了卡铂和培美曲塞治疗。她对一线化疗表现出显著反应，疾病进展后，又接受了吉西他滨和长春瑞滨的进一步化疗。她仍然存活，生存期出人意料地长。
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