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一项对南非与甲基苯丙胺相关的急性精神科住院病例的趋势和临床特征的回顾性研究。

A retrospective review of trends and clinical characteristics of methamphetamine-related acute psychiatric admissions in a South African context.

作者信息

Vos P J, Cloete K J, le Roux A, Kidd M, Jordaan G P

机构信息

Department of Psychiatry, University of Stellenbosch, Tygerberg, South Africa.

出版信息

Afr J Psychiatry (Johannesbg). 2010 Nov;13(5):390-4. doi: 10.4314/ajpsy.v13i5.63105.

Abstract

OBJECTIVE

Epidemiological studies indicate that methamphetamine (MA) abuse poses a major challenge to health in the Western Cape. The objectives of this study were to retrospectively assess the trends, clinical characteristics and treatment demand of MA-related admissions to a psychiatric ward in this region.

METHOD

The clinical records of patients admitted to an acute psychiatric admission ward at Tygerberg Hospital from 1 January 2002 to 30 June 2002 and 1 January 2006 to 30 June 2006, were retrospectively reviewed. Admission numbers including those of adolescent and adult substance users were compared for both study periods. Study samples comparing demographic profile, admission status, length of stay, psychopathology, treatment requirements and referral pattern to other disciplines between MA users and non-users were collected for the 2006 period.

RESULTS

There was a significant (p <0.01) increase in adolescent substance user admissions between the study periods. A significant (p <0.01) increase in adolescent and adult MA user admissions was also noted. MA users were significantly (p = 0.04) younger than non-MA users, whilst the former presented mainly with psychotic features associated with aggression, requiring involuntary admission of an average of 8 weeks. MA users required significantly (p = 0.007) more benzodiazepines compared to non-MA users.

CONCLUSION

Although MA use is relatively recent to the Western Cape, its adverse psychiatric effects and consequences have become a major challenge. These effects in both adolescent and adult patient populations and the associated impact on psychiatric services demand urgent intervention strategies as well as prospective study.

摘要

目的

流行病学研究表明,甲基苯丙胺(MA)滥用对西开普省的健康构成了重大挑战。本研究的目的是回顾性评估该地区精神科病房与MA相关入院病例的趋势、临床特征及治疗需求。

方法

回顾性分析2002年1月1日至2002年6月30日以及2006年1月1日至2006年6月30日期间在泰格堡医院急性精神科入院病房收治患者的临床记录。比较两个研究期间包括青少年和成年药物使用者在内的入院人数。收集2006年期间MA使用者与非使用者之间在人口统计学特征、入院状态、住院时间、精神病理学、治疗需求以及转介至其他科室模式等方面的研究样本。

结果

在研究期间,青少年药物使用者的入院人数显著增加(p<0.01)。青少年和成年MA使用者的入院人数也显著增加(p<0.01)。MA使用者的年龄显著低于非MA使用者(p = 0.04),前者主要表现为与攻击行为相关的精神病性特征,平均需要非自愿住院8周。与非MA使用者相比,MA使用者对苯二氮䓬类药物的需求量显著更高(p = 0.007)。

结论

尽管MA在西开普省的使用相对较新,但其不良精神影响和后果已成为一项重大挑战。青少年和成年患者群体中的这些影响以及对精神科服务的相关影响需要紧急干预策略以及前瞻性研究。

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