Roder U W, Markey F
Biacore, Pharmacia, Freiberg, Germany.
Methods Mol Med. 1998;13:531-54. doi: 10.1385/0-89603-485-2:531.
One of the most important classes of reagents for clinical diagnosis is antibodies, either in polyclonal preparations, as monoclonal antibodies (MAbs), or as customized reagents prepared by genetic engineering. The enormous range of antibodies produced by hybridoma and recombinant technologies, together with the requirements of clinical diagnosis for sensitivity and selectivity, make heavy demands on the processes of selecting and characterizing suitable antibody reagents.
临床诊断中最重要的一类试剂是抗体，包括多克隆制剂中的抗体、单克隆抗体（MAb）或通过基因工程制备的定制试剂。杂交瘤技术和重组技术产生的大量抗体，以及临床诊断对灵敏度和选择性的要求，对选择和鉴定合适抗体试剂的过程提出了很高的要求。
