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卡特里娜飓风过后,艾滋病毒/艾滋病感染者的CD4细胞计数变化。

Changes in CD4 count among persons living with HIV/AIDS following Hurricane Katrina.

作者信息

Robinson William T, Wendell Deborah, Gruber DeAnn

机构信息

School of Public Health, Louisiana State University Health Sciences Center, New Orleans, USA.

出版信息

AIDS Care. 2011 Jul;23(7):803-6. doi: 10.1080/09540121.2010.534437. Epub 2011 Jun 24.

Abstract

To examine the effects of Hurricane Katrina on the disease progression of persons living with HIV/AIDS (PLWH/A), CD4 counts during the 18 months immediately prior and subsequent to Katrina were obtained from the Louisiana Office of Public Health. PLWH/A were determined to be either non-residents of the New Orleans area, returning evacuees or evacuees who had returned to the area within 18 months. A mixed model repeated measures ANOVA showed significant effects for race, sex, age, year of diagnosis, and mode of exposure. A significant main effect for residence was found, as well as an interaction of residence by time of CD4 count (pre-Katrina vs. post-Katrina), indicating that, while non-returning evacuees had lower overall CD4 counts, the change in CD4 counts of non-returning evacuees dropped more sharply than those of the returning PLWH/A or non-residents. While these results point to a potential need for the population of PLWH/A who continue to be affected by Katrina, they also provide important data on the effect that large-scale disasters and stressful life events may have on individuals with chronic disease.

摘要

为研究卡特里娜飓风对艾滋病毒/艾滋病感染者(PLWH/A)疾病进展的影响,从路易斯安那州公共卫生办公室获取了卡特里娜飓风前后18个月内的CD4细胞计数。PLWH/A被确定为新奥尔良地区的非居民、返乡撤离者或在18个月内返回该地区的撤离者。混合模型重复测量方差分析显示,种族、性别、年龄、诊断年份和接触方式有显著影响。发现居住地有显著的主效应,以及居住地与CD4细胞计数时间(卡特里娜飓风前与卡特里娜飓风后)的交互作用,这表明,虽然未返乡的撤离者总体CD4细胞计数较低,但未返乡撤离者的CD4细胞计数下降幅度比返乡的PLWH/A或非居民更大。虽然这些结果表明受卡特里娜飓风持续影响的PLWH/A人群可能有潜在需求,但它们也提供了关于大规模灾难和压力性生活事件可能对慢性病患者产生何种影响的重要数据。

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