Suppr超能文献

非洲农村地区抗逆转录病毒治疗可及性的运营评估:以刚果民主共和国基桑图为例。

Operational assessment of access to ART in rural Africa: the example of Kisantu in Democratic Republic of the Congo.

作者信息

Van Rompaey Sara, Kimfuta Jaques, Kimbondo Pierre, Monn Cecilia, Buvé Anne

机构信息

Basel University, Brussels, Belgium.

出版信息

AIDS Care. 2011 Jun;23(6):686-93. doi: 10.1080/09540121.2010.532538.

Abstract

Despite the availability of large funds and considerable efforts to improve access to antiretroviral therapy (ART), coverage of treatment with ART remains low in Democratic Republic of the Congo (DRC). We identified the bottlenecks for adults' access to ART in a semi-rural health zone in DRC, compared ART coverage in the urban and rural area and described the outcomes and yield of different HIV testing settings. An operational model was used to examine bottlenecks in the flow of patients. The study period covered the start of the HIV care programme in April 2006, until December 2008. An estimated 505 People Living With HIV/AIDS (PLWHA), of whom 201 were in need of ART, lived in the health zone. The proportion of PLWHA in need of ART who were actually receiving ART was estimated at 53%. About 6451 adults were tested for HIV, 266 of them were HIV-positive and 163 accessed the HIV care programme. About 106 of the 126-159 eligible patients initiated ART. The main bottleneck was situated at HIV detection. Access to the HIV care programme for the patients testing HIV-positive was identified as the second biggest bottleneck. About 41% of the PLWHA identified in urban areas accessed the HIV care programme, versus 11% of the rural PLWHA, showing a serious inequity. The tuberculosis (TB) programme detected 75% of the total estimated 92 co-infected patients of the health zone. Only 13% of women testing positive in the Prevention of Mother-To-Child Transmission programme accessed the HIV care programme, showing that this bottleneck is greatly accentuated in this specific group. By testing all pregnant women and all TB patients in the health zone, 28% of all PLWHA could potentially be detected in a period of 33 months, showing its great potential in settings with a relatively low HIV prevalence.

摘要

尽管有大量资金可用,且为改善抗逆转录病毒疗法(ART)的可及性付出了巨大努力,但刚果民主共和国(DRC)的ART治疗覆盖率仍然很低。我们确定了刚果民主共和国一个半农村卫生区成人获得ART的瓶颈,比较了城乡地区的ART覆盖率,并描述了不同HIV检测环境的结果和产出。采用一种操作模型来检查患者流程中的瓶颈。研究期涵盖了2006年4月HIV护理项目启动至2008年12月。估计有505名艾滋病毒/艾滋病感染者(PLWHA)居住在该卫生区,其中201人需要ART治疗。估计实际接受ART治疗的有治疗需求的PLWHA比例为53%。约6451名成年人接受了HIV检测,其中266人呈HIV阳性,163人进入了HIV护理项目。126 - 159名符合条件的患者中约106人开始接受ART治疗。主要瓶颈在于HIV检测。HIV检测呈阳性的患者进入HIV护理项目被确定为第二大瓶颈。在城市地区确定的PLWHA中约41%进入了HIV护理项目,而农村PLWHA中这一比例为11%,显示出严重的不平等。结核病(TB)项目检测出了该卫生区估计92名合并感染患者中的75%。在预防母婴传播项目中检测呈阳性的女性中只有13%进入了HIV护理项目,表明这一瓶颈在这一特定群体中更为突出。通过对该卫生区所有孕妇和所有结核病患者进行检测,在33个月内有可能检测出所有PLWHA中的28%,显示出其在HIV流行率相对较低的环境中的巨大潜力。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验