Bone mineral disorder resulting from secondary distal renal tubular acidosis due to overlap syndrome (mixed connective tissue disorder) associated with coronary artery disease.

A 35 year old female presented with chronic bone mineral disorder which was due to secondary renal tubular acidosis--type 1 (RTA1). Serologically there was definite evidence of overlap syndrome (mixed connective tissue disease--M.C.T.D.), which was the cause for RTA1. During hospitalization she developed coronary artery thrombosis.