Elmhurst Hospital Center, Mount Sinai School of Medicine, New York 11373, USA.
Int J Psychiatry Med. 2010;40(4):399-411. doi: 10.2190/PM.40.4.d.
Validation of the Multicultural Quality of Life Index (MQLI), a 10-item self-rated generic multilingual quality of life (QOL) measure in ethnically-diverse diabetic patients.
Diabetic adult patients (n = 180) in New York City completed the MQLI, English or Spanish version. Its internal consistency, factorial structure, and construct validity were analyzed. Depression screening (PHQ-9) scores were used to divide subjects into two sub-samples with presumed different QOL levels.
A Cronbach's alpha of 0.92 demonstrated its internal consistency (English-version = 0.90, Spanish-version = 0.94). A one-single factor structure was documented (all items loadings > or = 0.64), accounting for 59% of the items variance in the total sample; similar results were found for each language version. Correlation of the MQLI and PHQ-9 scores yielded an r = -0.58. Mild negative correlations with self-disclosed diagnosis of depression or other mental disorders, diabetes duration, and abnormal sensation on foot exam were found, but were non-significant with other diabetes aspects (e.g., HbA1c, retinopathy). A significant difference (p < 0.001) between the scores of two subsamples with presumed different levels of QOL (means = 8.02 vs. 5.84) was found.
The MQLI demonstrated coherence around the QOL concept. It correlated significantly with mental health (particularly depression), duration of diabetes, and possible neuropathy, but not with some diabetes-related factors. Its use in diabetic care settings is recommended, possibly supplemented by QOL diabetic-specific instruments.
验证多文化生活质量指数（MQLI）的有效性，这是一种针对不同种族的糖尿病患者的 10 项自评式多语言生活质量（QOL）测量工具。
纽约市的成年糖尿病患者（n=180）完成了 MQLI、英语或西班牙语版本。分析了其内部一致性、因子结构和结构有效性。使用抑郁筛查（PHQ-9）评分将受试者分为两个亚组，假定其 QOL 水平不同。
Cronbach's alpha 为 0.92，表明其内部一致性（英语版本为 0.90，西班牙语版本为 0.94）。记录了一个单一的单因素结构（所有项目的负荷>或=0.64），占总样本中项目方差的 59%；两种语言版本均得出了类似的结果。MQLI 和 PHQ-9 评分之间的相关性为 r = -0.58。与自我报告的抑郁或其他精神障碍、糖尿病病程和足部检查异常感觉的轻度负相关，但与其他糖尿病方面（如 HbA1c、视网膜病变）无关。在假定 QOL 水平不同的两个亚组的分数之间发现了显著差异（p<0.001）（平均值分别为 8.02 与 5.84）。
MQLI 围绕 QOL 概念表现出一致性。它与心理健康（特别是抑郁）、糖尿病病程和可能的神经病变显著相关，但与一些糖尿病相关因素无关。建议在糖尿病护理环境中使用该工具，可能需要补充特定于 QOL 的糖尿病工具。
