Gauchotte Guillaume, Coffinet Laurent, Schmitt Emmanuelle, Bressenot Aude, Hennequin Virginie, Champigneulle Jacqueline, Vignaud Jean-Michel
Department of Pathology, Central University Hospital (CHU) Nancy, Nancy, France.
Fetal Pediatr Pathol. 2011;30(2):116-23. doi: 10.3109/15513815.2010.524690.
We report two cases of salivary gland anlage tumor (SGAT), a nasopharyngeal lesion that affects newborns. The first case concerned a male newborn, presenting respiratory distress secondary to a nasopharyngeal mass. The second case was diagnosed in a 6-week-old girl, suffering from respiratory difficulties due to a nasal cavity mass. A magnetic resonance imaging (MRI) in the second case revealed the presence of several small round and linear fluid-like areas. Histologically, both lesions were suggestive of SGAT, characterized by epithelial structures that blended with spindle-cells, drawing highly cellular nodules. Connective tissue between nodules contained squamous cystic nests and ducts.