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机器人辅助根治性前列腺切除术治疗经尿道前列腺切除术史患者的疗效。

Outcomes of robot-assisted radical prostatectomy in men with previous transurethral resection of prostate.

机构信息

Academic & Research, Urology, Medanta Institute of Kidney and Urology, Medanta - The Medicity, Gurgaon, Delhi, India.

出版信息

BJU Int. 2011 Nov;108(9):1501-5. doi: 10.1111/j.1464-410X.2011.10113.x. Epub 2011 Mar 10.

Abstract

OBJECTIVE

• To critically analyze and compare surgical, oncological and functional outcomes of robot-assisted radical prostatectomy (RARP) in patients with and without previous transurethral resection of prostate (TURP).

PATIENTS AND METHODS

• The study comprised 158 cases of RARP for clinically localized prostate cancer, including 26 cases that had undergone previous TURP (Group A). • Surgical, oncological and functional (short- and intermediate-term) outcomes of Group A were compared with 132 cases without previous TURP (Group B).

RESULTS

• Post TURP patients were found to have significantly greater blood loss (494 vs 324 mL) and a need for bladder neck reconstruction (26.7% vs 9.7%) compared to the non-TURP group. • Surgical time (189 vs 166 min), conversion rate, margin positivity rate and biochemical recurrence rate were also higher. • Incontinence rates were higher both at 6 (14% vs 11.8%) and 12 (25% vs 8%) months follow-up.

CONCLUSIONS

• RARP is feasible but challenging after TURP. It entails a longer operating time, greater operative difficulty and compromised oncological or continence outcomes. • These cases should be handled by an experienced robotic surgeon with the appropriate expertise.

摘要

目的

  • 分析和比较有和没有经尿道前列腺电切术(TURP)病史的患者行机器人辅助根治性前列腺切除术(RARP)的手术、肿瘤学和功能结果。

患者和方法

  • 本研究包括 158 例临床局限性前列腺癌的 RARP 病例,其中 26 例有 TURP 病史(A 组)。

  • 将 A 组的手术、肿瘤学和功能(短期和中期)结果与 132 例无 TURP 病史的患者(B 组)进行比较。

结果

  • 与非 TURP 组相比,TURP 后患者的出血量(494 与 324ml)和需要进行膀胱颈重建的比例(26.7%与 9.7%)显著更高。

  • 手术时间(189 与 166 分钟)、转换率、切缘阳性率和生化复发率也更高。

  • 在 6 个月(14%与 11.8%)和 12 个月(25%与 8%)随访时,尿失禁的发生率也更高。

结论

  • RARP 在 TURP 后是可行的,但具有挑战性。它需要更长的手术时间、更大的手术难度,并且肿瘤学或控尿结果受损。

  • 这些病例应由经验丰富的机器人外科医生处理,并具备相应的专业知识。

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