Department of Orthopaedics, Dartmouth-Hitchcock Medical Center, One Medical Center Dr., Lebanon, NH, USA.
Clin Orthop Relat Res. 2011 Jun;469(6):1721-7. doi: 10.1007/s11999-011-1848-4. Epub 2011 Mar 11.
Total ankle arthroplasty (TAA) implantation is increasing, as the potential for pain relief and restoration of function and risks are compared with those for ankle fusion. A previous analysis with a simple decision tree suggested TAA was cost-effective compared with ankle fusion. However, reevaluation is warranted with the availability of newer, more costly implants and longer-term patient followup data.
QUESTIONS/PURPOSES: Considering all direct medical costs regardless of the payer, we determined if TAA remains a cost-effective alternative to ankle fusion when updated evidence is considered.
Using a Markov model, we evaluated expected costs and quality-adjusted life years (QALY) for a 60-year-old hypothetical cohort with end-stage ankle arthritis treated with either TAA or ankle fusion. Costs were estimated from 2007 diagnosis-related group (DRG) and current procedural terminology (CPT) codes for each procedure. Rates were extracted from the literature. The incremental cost-effectiveness ratio (ICER), a measure of added cost divided by QALY gained for TAA relative to ankle fusion, was estimated. To identify factors affecting the value of TAA, sensitivity analyses were performed on all variables.
TAA costs $20,200 more than ankle fusion and resulted in 1.7 additional QALY, with an ICER of $11,800/QALY gained. Few variables in the sensitivity analyses resulted in TAA no longer being cost-effective.
Despite more costly implants and longer followup, TAA remains a cost-effective alternative to ankle fusion in a 60-year-old cohort with end-stage ankle arthritis.
与踝关节融合相比,全踝关节置换术(TAA)的植入率正在上升,因为它具有缓解疼痛、恢复功能的潜力,同时也存在一定的风险。之前的分析采用简单决策树表明,与踝关节融合相比,TAA 具有成本效益。然而,随着新型、更昂贵的植入物的出现以及更长期的患者随访数据的获得,需要重新评估。
问题/目的:无论支付方如何,我们考虑所有直接医疗成本,以确定在更新证据的情况下,TAA 是否仍然是踝关节融合的一种具有成本效益的替代方法。
使用马尔可夫模型,我们评估了 60 岁患有终末期踝关节关节炎的假想队列中,每位患者接受 TAA 或踝关节融合治疗的预期成本和质量调整生命年(QALY)。使用每个手术的 2007 年诊断相关组(DRG)和当前程序术语(CPT)代码来估算成本。从文献中提取了相关数据。增量成本效益比(ICER),即 TAA 相对于踝关节融合的额外成本与 QALY 增加的比值,被用来评估 TAA 的成本效益。为了确定影响 TAA 价值的因素,我们对所有变量进行了敏感性分析。
TAA 的成本比踝关节融合高出 20200 美元,且能获得 1.7 个额外的 QALY,其增量成本效益比为 11800 美元/QALY。敏感性分析中很少有变量导致 TAA 不再具有成本效益。
尽管植入物更昂贵,随访时间更长,但对于患有终末期踝关节关节炎的 60 岁患者,TAA 仍然是一种具有成本效益的踝关节融合替代方法。