Liláková D, Hejcmanová D, Krylová K
Ocní Klinika, Fakultni Nemocnice v Hradci Králové.
Cesk Slov Oftalmol. 2010 Oct;66(4):176-8.
The aim of this study is to characterize in detail the general health state in infants with retina treated due to retinopathy of prematurity and so to specify the group of premature infants at the highest risk, in which the closest ophthalmologist's attention needs to be paid in the screening for retinopathy in prematurely born babies. The study group consists of seven patients treated in the Perinatological Center of the Children Clinic of the Faculty Hospital in Hradec Králové, Czech Republic, E.U. during the period 2007-2009, in whom the retina was treated for retinopathy of prematurity. In all infants, who had to undergo the retinal treatment, the birth weight was less than 1000 g and a combination of bronchopulmonary dysplasia and infectious disease was present. In infants with the birth weight less than 1000 g, this combination was present in the range from 13.33 % to 23.68 %, which specifies the patients at the most risk. Unfavorable condition after the treatment was caused especially by serious infections and pulmonary complications presented before and after the treatment. Albeit we perform the screening of premature infants according to the current rules, the development shows that the highest attention should be paid to the infants with the birth weight less than 1000 g with complicating diseases as bronchopulmonary dysplasia and infections. For the ophthalmologist, these may be another clue to the presupposition of retinopathy of prematurity prognosis and seriousness besides the birth weight and gestational age.The complicating diseases facilitate to determine accurately the group of premature infants, which is at higher risk of higher grade of retinopathy.
本研究的目的是详细描述因早产儿视网膜病变接受视网膜治疗的婴儿的总体健康状况，从而明确风险最高的早产儿群体，在对早产婴儿进行视网膜病变筛查时，眼科医生需要对该群体给予最密切的关注。研究组由2007年至2009年期间在欧盟捷克共和国赫拉德茨克拉洛韦大学医院儿童诊所围产医学中心接受治疗的7例因早产儿视网膜病变接受视网膜治疗的患者组成。所有必须接受视网膜治疗的婴儿出生体重均低于1000g，且同时存在支气管肺发育不良和感染性疾病。在出生体重低于1000g的婴儿中，这种情况的发生率在13.33%至23.68%之间，这明确了风险最高的患者群体。治疗后出现不良状况尤其由治疗前后出现的严重感染和肺部并发症引起。尽管我们按照现行规则对早产儿进行筛查，但研究表明，应给予出生体重低于1000g且伴有支气管肺发育不良和感染等复杂疾病的婴儿最高度关注。对眼科医生而言，除了出生体重和孕周外，这些复杂疾病可能是预测早产儿视网膜病变预后和严重程度的另一条线索。这些复杂疾病有助于准确确定视网膜病变等级较高风险更高的早产儿群体。
