Interdepartementaal Stamcelinstituut, Katholieke Universiteit Leuven, O&N1, bus 804, Herestraat 49, 3000 Leuven, Belgium.
Best Pract Res Clin Haematol. 2011 Mar;24(1):3-11. doi: 10.1016/j.beha.2011.01.006. Epub 2011 Mar 4.
We here discuss the potency and characteristics of various adult derived adherent stem cells with special focus on multipotent adult progenitor cells (MAPC) isolated first in 2002 in our lab. We describe the potency of MAPC, our current understanding in relationship with novel insights gained in epigenetic modifications that increase cellular potency, and their possible clinical applications.
我们在这里讨论各种成体来源的贴壁干细胞的效力和特性，特别关注我们实验室于 2002 年首次分离的多能成年祖细胞（MAPC）。我们描述了 MAPC 的效力，以及我们目前对增加细胞效力的表观遗传修饰的新认识及其可能的临床应用。
