Department of Internal Medicine, Marshfield Clinic, WI, USA.
Ann Diagn Pathol. 2012 Jan;16(1):38-42. doi: 10.1016/j.anndiagpath.2010.11.009. Epub 2011 Mar 10.
Thymic cysts (congenital or acquired) are believed to account for 3% to 5% of all mediastinal masses. Multilocular thymic cysts are an acquired reactive inflammatory process arising within the thymus gland and are less common than the congenital unilocular type. Multilocular cysts have been reported in association with a variety of neoplastic, autoimmune, and infectious conditions. We report a case of a 23-year-old white man who presented with a 2-week history of progressive right-sided shoulder and chest pain. He was found to have an anterior mediastinal mass involving the thymus. This case of multilocular thymic cyst is particularly unique due to the presence of abundant epithelioid granulomata within the cyst, a finding that has not previously been emphasized as a histologic feature of these lesions, and one that expands the histopathologic differential diagnosis, warranting exclusion of infectious and autoimmune etiologies.
胸腺囊肿（先天性或获得性）占所有纵隔肿块的 3%至 5%。多房性胸腺囊肿是一种发生在胸腺内的获得性反应性炎症过程，比先天性单房性类型少见。多房性囊肿与多种肿瘤、自身免疫和感染性疾病有关。我们报告了 1 例 23 岁白人男性，其表现为进行性右侧肩部和胸痛 2 周。发现他有一个前纵隔肿块累及胸腺。这个多房性胸腺囊肿的病例特别独特，因为囊肿内有大量上皮样肉芽肿，这一发现以前并未被强调为这些病变的组织学特征之一，这扩大了组织病理学鉴别诊断，需要排除感染和自身免疫病因。
