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依托孕烯植入剂在青少年中的应用:临床方面评估。

Etonogestrel implant in adolescents: evaluation of clinical aspects.

机构信息

Family Planning Clinic, Department of Obstetrics and Gynecology, São Paulo Federal University, São Paulo ZIP 04040032, Brazil.

出版信息

Contraception. 2011 Apr;83(4):336-9. doi: 10.1016/j.contraception.2010.08.004. Epub 2010 Sep 24.

Abstract

BACKGROUND

This prospective noncomparative observational study evaluated the clinical aspects of adolescents who received an etonogestrel implant within 6 months of delivery.

STUDY DESIGN

The study population comprised 44 adolescents managed at the Family Planning Sector of São Paulo Federal University. The implant was inserted, on average, 102 days after delivery and patients were followed during 1 year. At each monthly visit to the clinic, the participants were weighed, had their blood pressure measured and were asked to report on symptoms experienced during the last 30 days.

RESULTS

Approximately one-third (38.6%) of the participants reported symptoms, mostly headaches. There were no complaints of dysmenorrhea, breast tenderness or lower leg edema throughout the 12 months of follow-up. Mean body weight dropped 1.2 kg on average, from 56.4 kg at implant insertion to 55.3 kg at the end of the 1-year period. Body mass index also decreased 0.5 kg/m(2) on average, although these changes did not reach statistical significance. Systolic and diastolic blood pressure remained unchanged throughout the study period. There were no pregnancies and none of the participants discontinued the method (528 women-months).

CONCLUSION

These findings suggest that the etonogestrel implant is a safe and effective contraceptive method that is well accepted by adolescents after a pregnancy.

摘要

背景

本前瞻性非对照观察性研究评估了在分娩后 6 个月内接受依托孕烯植入物的青少年的临床方面。

研究设计

研究人群包括在圣保罗联邦大学计划生育科管理的 44 名青少年。植入物平均在分娩后 102 天插入,患者在 1 年内接受随访。在每月到诊所就诊时,参与者会称重、测量血压,并被要求报告过去 30 天内经历的症状。

结果

约三分之一(38.6%)的参与者报告有症状,主要是头痛。在 12 个月的随访期间,没有出现痛经、乳房触痛或小腿水肿的投诉。平均体重平均下降 1.2 公斤,从植入时的 56.4 公斤下降到 1 年结束时的 55.3 公斤。体重指数也平均下降了 0.5kg/m²,尽管这些变化没有达到统计学意义。收缩压和舒张压在整个研究期间保持不变。没有怀孕,也没有参与者停止使用该方法(528 名女性-月)。

结论

这些发现表明,依托孕烯植入物是一种安全有效的避孕方法,在妊娠后被青少年广泛接受。

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