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依托孕诺酮皮下埋植剂用于产后青少年:出血模式、疗效和停药率。

Etonogestrel implant in postpartum adolescents: bleeding pattern, efficacy and discontinuation rate.

机构信息

Department of Obstetrics and Gynecology, Family Planning Clinic, São Paulo Federal University (UNIFESP), São Paulo, Brazil.

出版信息

Contraception. 2010 Sep;82(3):256-9. doi: 10.1016/j.contraception.2010.02.010. Epub 2010 Mar 29.

Abstract

BACKGROUND

The increasing rate of teenage pregnancies is a challenge to health professionals. New contraceptive methods have been developed to try to improve adherence in this group of patients. The study was conducted to evaluate the bleeding pattern, efficacy and discontinuation rate of etonogestrel implant (68 mg) inserted in postpartum adolescents.

STUDY DESIGN

The study population comprised 44 postpartum adolescents managed at the Family Planning Sector of São Paulo Federal University. The implant was inserted, on average, 102 days after delivery. Patients were followed prospectively during four 90-day periods.

RESULTS

All 44 patients completed the 12 months of follow-up, resulting in a study discontinuation rate of 0%. No implants were removed. There were no pregnancies during the study. After 1 year of use, frequent and prolonged bleeding were reported by less than 5% of the patients and amenorrhea occurred in 38.6% of the users. Laboratory parameters indicated a significant increase in hemoglobin and hematocrit among users.

CONCLUSION

These findings suggest that the etonogestrel implant is a safe and effective contraceptive method that is well accepted by adolescents after a pregnancy.

摘要

背景

青少年怀孕率的上升对卫生专业人员来说是一个挑战。已经开发出新的避孕方法,试图提高这组患者的依从性。本研究旨在评估产后青少年中植入的依托孕烯植入剂(68 毫克)的出血模式、疗效和停药率。

研究设计

研究人群包括在圣保罗联邦大学计划生育部门管理的 44 名产后青少年。植入物平均在分娩后 102 天插入。患者在四个 90 天期间进行前瞻性随访。

结果

所有 44 名患者均完成了 12 个月的随访,研究停药率为 0%。没有植入物被取出。研究期间没有怀孕。使用 1 年后,不到 5%的患者报告频繁和长时间出血,38.6%的使用者出现闭经。实验室参数表明使用者的血红蛋白和血细胞比容显著增加。

结论

这些发现表明,依托孕烯植入剂是一种安全有效的避孕方法,在妊娠后被青少年广泛接受。

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