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老年人心力衰竭的临床特征差异及预后预测因素。

Differential clinical characteristics and outcome predictors of acute heart failure in elderly patients.

机构信息

Area of Emergency Medicine, Hospital Universitario Central de Asturias, Emergency Medicine Investigation Group-HUCA, Oviedo, Spain.

出版信息

Int J Cardiol. 2012 Feb 23;155(1):81-6. doi: 10.1016/j.ijcard.2011.02.031. Epub 2011 Mar 12.

Abstract

OBJECTIVE

We determined the clinical-epidemiological characteristics and prognostic factors of early mortality and re-consultation in an elderly population attending the hospital emergency department (HED) for acute heart failure (AHF).

PATIENTS AND METHODS

A prospective, observational, non interventional study including all the patients with AHF attended in the Spanish's HED. Two groups were defined: elderly (≥ 80 years) and controls (< 80 years).

VARIABLES

demographic characteristics, comorbidity, degree of cardiac involvement, previous treatment, symptoms and signs of the AHF episode, precipitating factors, treatment in the HED and outcome.

OUTCOME VARIABLES

mortality and re-consultation within 30 days.

RESULTS

Of the 942 patients included, 455 of whom were elderly (48.3%). In this elderly population female sex, auricular fibrillation and a history of ictus and a poor functional status predominated. The type of ventricular dysfunction was unknown in 70%. No main differences in the presentation of AHF were found between the two groups. Mortality and re-consultation to the HED within 30 days were similar in both groups. While several factors were identified to be related to mortality or re-consultation in control group, in the elderly group it was more difficult to identify patients who will die or re-consult to the HED within the following 30 days. Only respiratory insufficiency on arrival to the HED was found to predict a greater probability of death (OR 3.55; CI95% 1.39-9.11).

CONCLUSIONS

AHF in elderly patients presents some differential characteristics and, most importantly, it is more difficult to identify which of these patients will die or re-consult in the short-term.

摘要

目的

我们确定了在因急性心力衰竭(AHF)就诊于医院急诊部(HED)的老年人群中,早期死亡率和再就诊的临床流行病学特征和预后因素。

患者和方法

一项前瞻性、观察性、非干预性研究,纳入了所有在西班牙 HED 就诊的 AHF 患者。定义了两组:老年(≥ 80 岁)和对照组(< 80 岁)。

变量

人口统计学特征、合并症、心脏受累程度、既往治疗、AHF 发作的症状和体征、诱发因素、HED 中的治疗和结局。

结局变量

30 天内的死亡率和再就诊率。

结果

在纳入的 942 名患者中,455 名(48.3%)为老年人。在这个老年人群中,女性、心房颤动和中风史以及较差的功能状态更为常见。70%的患者心室功能障碍类型未知。两组之间 AHF 的表现没有发现主要差异。两组之间 30 天内的死亡率和再就诊至 HED 的情况相似。虽然在对照组中确定了几个与死亡率或再就诊相关的因素,但在老年组中,更难以确定在接下来的 30 天内死亡或再就诊至 HED 的患者。只有到达 HED 时的呼吸衰竭被发现可预测更大的死亡概率(OR 3.55;95%CI95%1.39-9.11)。

结论

老年患者的 AHF 存在一些不同的特征,最重要的是,更难以确定这些患者中哪些患者在短期内会死亡或再就诊。

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