Service Gynécologie Obstétrique, Hôpital Bicêtre, Kremlin Bicêtre, France.
Hum Reprod. 2011 Jul;26(7):1730-4. doi: 10.1093/humrep/der056. Epub 2011 Mar 11.
The aim of this study was to describe the surgical approach to, and evaluate the reproductive outcome of, a T-shaped uterus.
The study included 97 women who were eligible for hysteroscopic surgery, by either monopolar or bipolar electrosurgical instruments. All had diagnostic hysteroscopy 2 months afterwards to assess the success of the procedure and determine whether any synechiae were present.
Forty-eight women (49.5%) became pregnant after metroplasty. The overall live birth rate per pregnancy before surgery was 0%; for these patients, it increased to 73%, and their miscarriage rate fell from 78 to 27% (P < 0.05). For all 57 pregnancies in 48 women, the ectopic pregnancy rate was 9% (n = 5), the miscarriage rate 28% (n = 16), the preterm delivery rate 14% (n = 8), the term delivery rate 49% (n = 28) and the live birth rate was 63% (n = 36).
Hysteroscopic metroplasty improves the live birth rate for women with a T-shaped uterus and a history of primary infertility, recurrent abortion or preterm delivery, although it is not a treatment of infertility.
本研究旨在描述 T 形子宫的手术方法,并评估其生殖结局。
该研究纳入了 97 名符合宫腔镜手术条件的女性,采用单极或双极电外科器械进行手术。所有患者在 2 个月后进行诊断性宫腔镜检查,以评估手术的成功率,并确定是否存在粘连。
48 名女性(49.5%)在子宫整形术后怀孕。手术前的整体活产率为 0%;对于这些患者,活产率增加到 73%,流产率从 78%降至 27%(P<0.05)。在 48 名女性的 57 次妊娠中,异位妊娠率为 9%(n=5),流产率为 28%(n=16),早产率为 14%(n=8),足月产率为 49%(n=28),活产率为 63%(n=36)。
宫腔镜子宫整形术可提高 T 形子宫伴原发性不孕、复发性流产或早产史女性的活产率,但它并不是治疗不孕的方法。