Grollier G, Troussard X, Scanu P, Voglimacci M, Gofard M, Lassaigne D, Leporrier M, Potier J C
Service de soins intensifs de cardiologie, Centre hospitalier universitaire, Caen.
Presse Med. 1990 Apr 14;19(15):715-8.
Selective cardiac involvement by a malignant non-Hodgkin's lymphoma (primary lymphoma of the heart) is extremely rare. Cardiac lesions occurring in the course of a malignant non-Hodgkin's lymphoma (secondary lymphoma of the heart) are found at autopsy in about 10 per cent of the cases. Secondary lymphoma of the heart may involve all cardiac structures, but lesions of the right heart, and particularly the right atrium, are predominant. Clinical manifestations are usually non-specific and appear at a late stage, reflecting diffuse involvement. When the malignant non-Hodgkin's lymphoma is known, systematic two-dimensional echocardiography should easily detect the lymphomatous cardiac infiltration, irrespective of the presence or absence of symptoms. When the malignant non-Hodgkin's lymphoma is unknown, only histology can show that the heart tumour is a lymphoma, evaluate its extension and confirm that it is limited to the cardiac walls, provided the disease is treated at an early stage, prolonged complete remissions are observed after chemotherapy and/or radiotherapy.
恶性非霍奇金淋巴瘤对心脏的选择性累及（原发性心脏淋巴瘤）极为罕见。在恶性非霍奇金淋巴瘤病程中出现的心脏病变（继发性心脏淋巴瘤），尸检发现约10%的病例存在此类病变。继发性心脏淋巴瘤可累及所有心脏结构，但右心病变，尤其是右心房病变最为常见。临床表现通常无特异性，且出现在疾病晚期，反映出弥漫性累及。当已知患有恶性非霍奇金淋巴瘤时，无论有无症状，系统性二维超声心动图应能轻易检测到淋巴瘤对心脏的浸润。当恶性非霍奇金淋巴瘤未知时，只有组织学检查才能表明心脏肿瘤是淋巴瘤，评估其范围，并确认其局限于心脏壁，前提是疾病在早期得到治疗，化疗和/或放疗后可观察到长期完全缓解。
