Chicago Medical School, Naperville, IL 60540, USA.
Am J Ther. 2012 Jan;19(1):e21-4. doi: 10.1097/MJT.0b013e3181e70c49.
Many studies have noted a correlation between obstructive sleep apnea (OSA) and atrial fibrillation (AF). Although there is a need for large randomized control trials, the present data are quite convincing and can be used to improve current treatment procedures. Reviews, randomized control trials, and meta-analyses were obtained using electronic search strategies such as Medline and Cochrane Library. References of electronically obtained studies were then used to conduct hand searches for additional relevant studies. Sources were deemed relevant if they discussed the relationship between AF and OSA in respect to incidence, mechanism, recurrence, or treatment. Selected sources were then stratified on the basis of quality. Correlations between OSA and AF are present, and OSA seems to lend itself to the development, progression, and post-ablation recurrence of AF. Treatment of OSA before ablation can help reduce AF recurrence, allowing for more efficient treatment of AF. It is thus important for physicians to monitor AF patients for OSA and monitor those with OSA for AF.
许多研究都指出阻塞性睡眠呼吸暂停(OSA)与心房颤动(AF)之间存在相关性。尽管需要进行大规模的随机对照试验,但目前的数据相当有说服力,可以用于改进当前的治疗程序。使用 Medline 和 Cochrane Library 等电子搜索策略获取综述、随机对照试验和荟萃分析。然后,利用电子获取研究的参考文献进行额外相关研究的手工搜索。如果研究讨论了 AF 与 OSA 之间在发病率、机制、复发或治疗方面的关系,则认为这些研究具有相关性。然后根据质量对选定的来源进行分层。OSA 与 AF 之间存在相关性,OSA 似乎有助于 AF 的发展、进展和消融后复发。消融前治疗 OSA 有助于减少 AF 复发,从而更有效地治疗 AF。因此,医生监测 AF 患者的 OSA 并监测患有 OSA 的患者的 AF 非常重要。