IQ Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Int J Gen Med. 2011 Jan 23;4:85-90. doi: 10.2147/IJGM.S15231.
The present study reports on the biochemical validation of the self-reported smoking status of patients with chronic obstructive pulmonary disease (COPD). The objective is to establish the proportion of overestimation of self-reported success rates.
A cross-sectional smoking-status validation study including 60 patients with COPD who reported that they had stopped smoking. In the analysis of urine samples, a cut-off point of 50 ng/mL of cotinine was used.
At the time of biochemical validation, 55 patients reported that they had quit smoking while five patients resumed smoking. Smoking status was biochemically confirmed for 43 patients (78%) and 12 patients (22%) were classified as smokers. The sensitivity of the self- report of smoking was 29% and the specificity was 100%.
Many primary care patients with COPD do not provide valid information on their smoking status, which hamper adequate therapeutic interventions. Integration of biochemical validation in daily care could overcome this problem, but may harm the doctor-patient relationship.
本研究报告了慢性阻塞性肺疾病（COPD）患者自我报告吸烟状况的生化验证情况。目的是确定自我报告成功率过高的比例。
这是一项包括 60 名报告已戒烟的 COPD 患者的横断面吸烟状况验证研究。在尿液样本分析中，使用可替宁 50ng/ml 的截断值。
在生化验证时，55 名患者报告已戒烟，而 5 名患者恢复吸烟。有 43 名患者（78%）的吸烟状况得到了生化证实，而 12 名患者（22%）被归类为吸烟者。自我报告吸烟的敏感性为 29%，特异性为 100%。
许多初级保健的 COPD 患者不能提供其吸烟状况的有效信息，这阻碍了适当的治疗干预。在日常护理中整合生化验证可以解决这个问题，但可能会损害医患关系。
