Cardiology Department, Tor Vergata University Hospital of Rome, Viale Oxford 81, 00133 Rome, Italy.
Cardiol Res Pract. 2011 Mar 3;2011:198653. doi: 10.4061/2011/198653.
No previous reports are available about the potential dramatic effects resulting from the combination of acquired long QT interval not associated to bradycardia and myocardial ischemia. We report the case of a man that during acute necrotic pancreatitis presented QT interval prolongation without bradycardia, TdP, and two episodes of cardiac arrest. A coronary angiogram revealed a subocclusive stenosis of left anterior descending coronary artery, treated with a percutaneous coronary intervention. After myocardial revascularization, even in presence of long QT interval, no arrhythmic events occurred suggesting the key role of myocardial ischemia in triggering TdP in acquired long QT even without bradycardia. ECG performed six months later, after complete recovery from pancreatitis, showed a normal QT interval.
目前尚无关于获得性 QT 间期延长(与心动过缓无关)和心肌缺血联合导致潜在剧烈影响的相关报道。我们报告了一例急性坏死性胰腺炎患者,该患者在没有心动过缓、TdP 和两次心脏骤停的情况下出现 QT 间期延长。冠状动脉造影显示左前降支冠状动脉次闭塞性狭窄,行经皮冠状动脉介入治疗。心肌再血管化后,即使存在 QT 间期延长,也未发生心律失常事件,提示心肌缺血在触发获得性 QT 间期延长时即使没有心动过缓也可引发 TdP 的关键作用。胰腺炎完全恢复后 6 个月进行的心电图检查显示 QT 间期正常。