Kieslichová Eva, Rocen Milan, Franková Sona, Trunecka Pavel
Institut klinické a experimentální medicíny v Praze, Transplantcentrum, Klinika anesteziologie, resuscitace a intenzivní péce.
Cas Lek Cesk. 2011;150(1):24-30.
Acute liver failure is a life threatening illness whose mortality rate remains high. For the survival an early diagnosis is crucial as well as the use of specific and supportive therapy and the determination of patient's need for urgent liver transplantation. At the first signs of the disease progression it is necessary to contact a transplantation centre. The patient with acute liver failure should be admitted to intensive care unit of a hospital capable to perform liver transplantation. Liver transplantation is limited by the availability of organs. It is possible to expand the time required for spontaneous liver regeneration or transplantation by using liver supporting systems. The therapy of the acute liver failure is multidisciplinary and should be performed in specialized centers.
急性肝衰竭是一种危及生命的疾病，其死亡率仍然很高。为了患者存活，早期诊断至关重要，同时还需要使用特异性和支持性治疗方法，并确定患者是否急需肝移植。在疾病进展的最初迹象出现时，必须联系移植中心。急性肝衰竭患者应入住有能力进行肝移植的医院的重症监护病房。肝移植受器官供应的限制。使用肝脏支持系统可以延长自发肝再生或移植所需的时间。急性肝衰竭的治疗是多学科的，应在专业中心进行。
