Dipartimento di Medicina Interna e Specialità Mediche, UOC Reumatologia, Sapienza Università di Roma, Viale del Policlinico 155, 00161 Rome, Italy.
Rheumatology (Oxford). 2011 Aug;50(8):1409-13. doi: 10.1093/rheumatology/ker111. Epub 2011 Mar 15.
To investigate the role of a new hybrid imaging modality, integrated in the US equipment and derived by a real-time MRI and US fusion process, in the hand and wrist joints of a small group of rheumatic patients.
Consecutive patients with OA and RA with hand and wrist involvement were studied. Clinical assessment, physical examination, hand and wrist radiography and laboratory tests were carried out. After performing 0.2T MRI (T₁, T₂ and short time inversion recovery sequences) of the dominant hand and wrist, images were recorded in a US machine equipped with a virtual navigator system. Ultrasonography was performed in the same joints using an 18 MHz linear probe. Image MRI/US superposition was carried out, with real-time contemporary visualization of the US and related MRI images. Randomly selected stored images of different joints were subsequently re-analysed by a different operator. Concordance between the static and dynamic evaluations was assessed.
Nine patients (six with OA and three with RA) were studied. The real-time MRI/US overlap provided fusion images of both tools. A striking concordance in the visualization of the bony profile was found with evidence of pronounced osteophytes in OA and bone erosions in RA. The analysis of stored selected images demonstrated a high concordance between real-time and static assessment.
MRI/US fusion imaging gives a composite set of information with accurate anatomical correlations.
研究一种新的混合成像方式在少数风湿患者手和腕关节中的作用。
对伴有手和腕关节受累的 OA 和 RA 患者进行研究。进行临床评估、体格检查、手部和腕部 X 线摄影和实验室检查。对优势手和腕进行 0.2T MRI（T₁、T₂ 和短时间反转恢复序列）检查后，在配备虚拟导航系统的 US 机上记录图像。在同一关节中使用 18MHz 线性探头进行超声检查。进行 MRI/US 图像叠加，实时同时可视化 US 和相关 MRI 图像。随后，由另一位操作人员对不同关节的随机存储图像进行重新分析。评估静态和动态评估之间的一致性。
共研究了 9 例患者（6 例 OA，3 例 RA）。实时 MRI/US 重叠提供了两种工具的融合图像。在骨轮廓的可视化方面存在显著一致性，OA 中存在明显的骨赘，RA 中存在骨侵蚀。对存储的选定图像的分析表明，实时和静态评估之间具有高度一致性。
MRI/US 融合成像提供了具有准确解剖相关性的综合信息。
