基于适体的信号开启和多重传感平台，可用于在一个检测点同时进行蛋白质和小分子的电子检测。
An aptamer-based signal-on and multiplexed sensing platform for one-spot simultaneous electronic detection of proteins and small molecules.
机构信息
Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
出版信息
Chem Commun (Camb). 2011 Apr 28;47(16):4733-5. doi: 10.1039/c1cc10240k. Epub 2011 Mar 16.
PMID:21409285
Abstract
One-spot signal-on and simultaneous electronic detection of lysozyme and adenosine is achieved based on target-induced release of aptamers and back-filling hybridization of the resulting single stranded DNAs with redox-tags conjugated aptamers.
摘要
基于适配体引发的释放和带有氧化还原标签的适配体对所得单链 DNA 的反向填充杂交，实现了溶菌酶和腺苷的单点信号开启和同时电子检测。
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