Shah S Sadiq, Noor Lubna, Sawar Shah, Awan Zahid Aslam, Hafeezullah Muhammad, Khan Sher Bahadar
Department of Cardiology, Bacha Khan Medical College, Mardan, Pakistan.
J Ayub Med Coll Abbottabad. 2010 Jan-Mar;22(1):121-4.
Renal artery stenosis (RAS) is a common finding in patients undergoing coronary angiography. We designed this study to look for the frequency and any predictors of renal artery stenosis in patients with coronary artery disease (CAD).
A total of 201 consecutive patients with CAD confirmed by coronary angiography underwent an abdominal aortogram in the same sitting to screen for RAS. Patient demographics and co-morbidities were analysed for any association with RAS.
Forty-one of the patients were female (20.4%); ninety patients were hypertensive (44.8%); 49 patients (24.4%) were smokers; 19 patients (9.5%) had renal insufficiency; 88 patients (43.8%) had high cholesterol levels; 44 patients (21.9%) were diabetic. Thirty-two patients (15.9%) had single coronary artery disease, 59 patients (29.4%) had two vessel disease, and 110 patients (54.7%) had three vessel disease. Significant renal artery stenosis (> or = 50% stenosis) was present in 26 patients (12.9%). Among the variables studied, only female gender was found to be associated with a higher frequency of renal artery stenosis (24.39% vs 10.0%, p = 0.01).
The frequency of renal artery stenosis in patients with coronary artery disease is 12.9%. Female gender is associated with a higher frequency of renal artery stenosis in patients with CAD.
肾动脉狭窄(RAS)在接受冠状动脉造影的患者中是常见发现。我们设计本研究以探寻冠心病(CAD)患者中肾动脉狭窄的发生率及任何预测因素。
总共201例经冠状动脉造影确诊为CAD的连续患者在同一次检查中接受腹部主动脉造影以筛查RAS。分析患者的人口统计学特征和合并症与RAS的任何关联。
41例患者为女性(20.4%);90例患者患有高血压(44.8%);49例患者(24.4%)吸烟;19例患者(9.5%)有肾功能不全;88例患者(43.8%)胆固醇水平高;44例患者(21.9%)患有糖尿病。32例患者(15.9%)有单支冠状动脉病变,59例患者(29.4%)有双支血管病变,110例患者(54.7%)有三支血管病变。26例患者(12.9%)存在显著肾动脉狭窄(狭窄≥50%)。在所研究的变量中,仅发现女性与肾动脉狭窄的较高发生率相关(24.39%对10.0%,p = 0.01)。
冠心病患者中肾动脉狭窄的发生率为12.9%。女性与冠心病患者中肾动脉狭窄的较高发生率相关。