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冠心病患者肾动脉狭窄的发生率及预测因素

Frequency and predictors of renal artery stenosis in patients with coronary artery disease.

作者信息

Shah S Sadiq, Noor Lubna, Sawar Shah, Awan Zahid Aslam, Hafeezullah Muhammad, Khan Sher Bahadar

机构信息

Department of Cardiology, Bacha Khan Medical College, Mardan, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2010 Jan-Mar;22(1):121-4.

Abstract

BACKGROUND

Renal artery stenosis (RAS) is a common finding in patients undergoing coronary angiography. We designed this study to look for the frequency and any predictors of renal artery stenosis in patients with coronary artery disease (CAD).

METHODS

A total of 201 consecutive patients with CAD confirmed by coronary angiography underwent an abdominal aortogram in the same sitting to screen for RAS. Patient demographics and co-morbidities were analysed for any association with RAS.

RESULTS

Forty-one of the patients were female (20.4%); ninety patients were hypertensive (44.8%); 49 patients (24.4%) were smokers; 19 patients (9.5%) had renal insufficiency; 88 patients (43.8%) had high cholesterol levels; 44 patients (21.9%) were diabetic. Thirty-two patients (15.9%) had single coronary artery disease, 59 patients (29.4%) had two vessel disease, and 110 patients (54.7%) had three vessel disease. Significant renal artery stenosis (> or = 50% stenosis) was present in 26 patients (12.9%). Among the variables studied, only female gender was found to be associated with a higher frequency of renal artery stenosis (24.39% vs 10.0%, p = 0.01).

CONCLUSIONS

The frequency of renal artery stenosis in patients with coronary artery disease is 12.9%. Female gender is associated with a higher frequency of renal artery stenosis in patients with CAD.

摘要

背景

肾动脉狭窄(RAS)在接受冠状动脉造影的患者中是常见发现。我们设计本研究以探寻冠心病(CAD)患者中肾动脉狭窄的发生率及任何预测因素。

方法

总共201例经冠状动脉造影确诊为CAD的连续患者在同一次检查中接受腹部主动脉造影以筛查RAS。分析患者的人口统计学特征和合并症与RAS的任何关联。

结果

41例患者为女性(20.4%);90例患者患有高血压(44.8%);49例患者(24.4%)吸烟;19例患者(9.5%)有肾功能不全;88例患者(43.8%)胆固醇水平高;44例患者(21.9%)患有糖尿病。32例患者(15.9%)有单支冠状动脉病变,59例患者(29.4%)有双支血管病变,110例患者(54.7%)有三支血管病变。26例患者(12.9%)存在显著肾动脉狭窄(狭窄≥50%)。在所研究的变量中,仅发现女性与肾动脉狭窄的较高发生率相关(24.39%对10.0%,p = 0.01)。

结论

冠心病患者中肾动脉狭窄的发生率为12.9%。女性与冠心病患者中肾动脉狭窄的较高发生率相关。

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