Tarnaris Andrew, Toma Ahmed K, Watkins Laurence D, Kitchen Neil D
Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London WC 1N 3BG, UK.
Clin Neurol Neurosurg. 2011 Jul;113(6):477-9. doi: 10.1016/j.clineuro.2011.02.008. Epub 2011 Mar 15.
The visual and headache outcomes in patients with idiopathic intracranial hypertension (IIH) undergoing cerebrospinal fluid diversion with a lumboperitoneal (LPS) or ventriculoperitoneal shunting (VPS) have not been well reported. The aims of this study were to: (a) to assess outcomes of CSF diversion in IIH, (b) to understand influence of the type of shunt in outcomes, and (c) to understand factors predisposing in shunt failure.
The medical records of 34 patients who underwent cerebrospinal fluid diversion (CSFD) between 1996 and 2007 were retrieved and epidemiological and clinical data was collected.
The mean age was 35 (±7.9) years. Thirty-four patients underwent 63 shunt placements in total. 85% follow-up was achieved. The mean follow-up for the entire group was 28.9 (±31.8) months. Headaches improved more than visual disturbances. There was no significant difference between the groups that received a VPS and those receiving an LPS in both headache and visual outcomes. The rate of complications was 20.5% and the need for revision was 35% for the whole group. Patients with LPS suffered more complications and first time revisions than patients with VPS. No factor recorded could predict the need for revision or final outcomes. The shunts of patients receiving a VPS tend to survive longer than those receiving primarily an LPS, however the difference is not statistically significant.
Predicting which patients will improve is not possible at present. The influence of site diversion is not critical but patients with VPS have less complications and revisions than those receiving a LPS.
关于特发性颅内高压(IIH)患者行腰大池-腹腔分流术(LPS)或脑室-腹腔分流术(VPS)进行脑脊液分流后的视力和头痛结局,尚未有充分报道。本研究的目的是:(a)评估IIH患者脑脊液分流的结局;(b)了解分流类型对结局的影响;(c)了解导致分流失败的因素。
检索1996年至2007年间34例行脑脊液分流术(CSFD)患者的病历,并收集流行病学和临床数据。
平均年龄为35(±7.9)岁。34例患者共进行了63次分流置管。随访率达85%。整个组的平均随访时间为28.9(±31.8)个月。头痛改善情况优于视力障碍。接受VPS和接受LPS的两组在头痛和视力结局方面均无显著差异。整个组的并发症发生率为20.5%,需要翻修的比例为35%。接受LPS的患者比接受VPS的患者并发症更多,首次翻修的情况也更多。记录的任何因素都无法预测是否需要翻修或最终结局。接受VPS的患者的分流管存活时间往往比主要接受LPS的患者更长,然而差异无统计学意义。
目前无法预测哪些患者会改善。分流部位的影响并不关键,但接受VPS的患者比接受LPS的患者并发症和翻修情况更少。