Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA.
Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA.
Oper Neurosurg (Hagerstown). 2021 Jul 15;21(2):57-62. doi: 10.1093/ons/opab106.
CSF shunting is among the most widely utilized interventions in patients with idiopathic intracranial hypertension (IIH). Ventriculoperitoneal shunting (VPS) and lumboperitoneal shunting (LPS) are 2 possible treatment modalities.
To evaluate and compare complications, malfunction, infection, and revision rates associated with VPS compared to LPS.
Electronic medical records were reviewed to identify baseline and treatment characteristics for patients diagnosed with IIH treated with VPS or LPS.
A total of 163 patients treated with either VPS (74.2%) or LPS (25.8%) were identified. The mean follow-up was 35 mo. Shunt revision was required in 40.9% of patients. There was a nonsignificant higher rate of revision with LPS (52.4%) than VPS (36.4%, P = .07). In multivariate analysis, increasing patient age was associated with higher odds of shunt revision (P = .04). LPS had higher odds of shunt revision, yet this association was not significant (P = .06). Shunt malfunction was the main indication for revision occurring in 32.7%, with a significantly higher rate with LPS than VPS (P = .03). In total, 15 patients had shunt infection (9.4% VPS vs 12.2% LPS P = .50). The only significant predictor of procedural infection was the increasing number of revisions (P = .02).
The incidence of shunt revision was 40.9%, with increasing patient age as the sole predictor of shunt revision. The incidence of shunt malfunction was significantly higher in patients undergoing LPS, while there was no significant difference in the incidence of shunt infection between the 2 modalities.
脑脊髓液分流术是治疗特发性颅内高压(IIH)患者最广泛应用的干预手段之一。脑室-腹腔分流术(VPS)和腰-腹腔分流术(LPS)是两种可能的治疗方式。
评估和比较 VPS 与 LPS 相关的并发症、故障、感染和翻修率。
回顾性电子病历,以确定诊断为 IIH 并接受 VPS 或 LPS 治疗的患者的基线和治疗特征。
共发现 163 例接受 VPS(74.2%)或 LPS(25.8%)治疗的患者。平均随访时间为 35 个月。40.9%的患者需要进行分流管翻修。LPS 组(52.4%)的翻修率明显高于 VPS 组(36.4%,P=0.07),但差异无统计学意义。多变量分析显示,患者年龄的增加与分流管翻修的可能性更高相关(P=0.04)。LPS 组发生分流管故障的风险更高,但差异无统计学意义(P=0.06)。分流管故障是翻修的主要原因,占 32.7%,LPS 组的发生率明显高于 VPS 组(P=0.03)。共有 15 例患者发生分流管感染(VPS 组 9.4%,LPS 组 12.2%,P=0.50)。唯一显著预测感染的因素是翻修次数的增加(P=0.02)。
分流管翻修的发生率为 40.9%,患者年龄的增加是唯一预测分流管翻修的因素。LPS 组的分流管故障发生率明显更高,而两种方式之间的分流管感染发生率无显著差异。