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碳纤维在大鼠腹壁缺损修复中的应用。

Use of carbon fibers for repair of abdominal-wall defects in rats.

作者信息

Morris D M, Haskins R, Marino A A, Misra R P, Rogers S, Fronczak S, Albright J A

机构信息

Department of Surgery, School of Medicine, Louisiana State University Medical Center, Shreveport.

出版信息

Surgery. 1990 Jun;107(6):627-31.

PMID:2141192
Abstract

Carbon in the form of 8-micron fibers induces growth of connective tissue. The purpose of this study was to measure and histologically characterize tissue ingrowth occurring in carbon fibers implanted for up to 12 months in abdominal-wall defects in rats, compared with polypropylene mesh. Carbon fibers induced significantly more tissue ingrowth than polypropylene mesh at 6 to 12 months postoperatively. The predominant tissues associated with carbon fibers and polypropylene mesh were dense connective tissue and fat, respectively. Fragmentation of the implants did not occur, and implant debris was not found in the regional lymph nodes. Carbon fibers are potentially useful for reinforcing abdominal-wall defects.

摘要

8微米纤维形式的碳可诱导结缔组织生长。本研究的目的是测量大鼠腹壁缺损处植入长达12个月的碳纤维与聚丙烯网相比,组织向内生长的情况并进行组织学特征分析。术后6至12个月,碳纤维诱导的组织向内生长明显多于聚丙烯网。与碳纤维和聚丙烯网相关的主要组织分别是致密结缔组织和脂肪。植入物未发生破碎,区域淋巴结中也未发现植入物碎片。碳纤维在加强腹壁缺损方面可能具有潜在用途。

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