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[一名脑出血男性患者的应激性心肌病]

[Tako-tsubo cardiomyopathy in a man with cerebral haemorrhage].

作者信息

Smedra-Kaźmirska Anna, Barzdo Maciej, Kowalski Jan, Szram Stefan, Berent Jarosław

机构信息

Zakład Medycyny Sadowej, Uniwersytet Medyczny w Łodzi.

出版信息

Anestezjol Intens Ter. 2010 Apr-Jun;42(2):85-9.

Abstract

BACKGROUND

The Tako-Tsubo syndrome is characterized by a transient left ventricular dysfunction in the absence of obstructive coronary disease, typically precipitated by severe emotional or physical stress. It is characterized by a balloon-like left ventricular appearance on angiography, ECG changes, and elevated cardiac biomarkers. We describe a case, where Tako-Tsubo cardiomyopathy was diagnosed in a patient with subarachnoid haemorrhage.

CASE REPORT

A 57-year-old man was brought to the hospital after cardiac arrest and successful resuscitation. After admission, echocardiography was performed that revealed marked impairment of contractility of the left ventricle with akinesis of the apex, interventricular septum, and anterior wall. Subsequent coronary angiography revealed neither coronary pathology nor pulmonary embolism; however, ventriculography showed typical dynamics of the Tako-Tsubo syndrome. Because of a deep cerebral coma (GSG 3), a CT-scan was performed that revealed subarachnoid haemorrhage with a haemotoma in the left temporal lobe, together with symptoms of massive cerebral oedema. The patient died eight days later despite vigorous intensive care. During the autopsy, a ruptured aneurysm of the left central cerebral artery was found.

CONCLUSIONS

The Tako-Tsubo syndrome may occur not only during serious stress but also after resuscitation of cardiac arrest following cerebral bleeding.

摘要

背景

应激性心肌病的特征是在无阻塞性冠状动脉疾病的情况下出现短暂性左心室功能障碍,通常由严重的情绪或身体应激诱发。其特征为血管造影显示左心室呈气球样外观、心电图改变以及心脏生物标志物升高。我们描述了一例在蛛网膜下腔出血患者中诊断出应激性心肌病的病例。

病例报告

一名57岁男性在心脏骤停并成功复苏后被送往医院。入院后进行了超声心动图检查,结果显示左心室收缩功能明显受损,心尖、室间隔和前壁运动减弱。随后的冠状动脉造影未发现冠状动脉病变或肺栓塞;然而,心室造影显示出应激性心肌病的典型动态变化。由于患者处于深度脑昏迷状态(格拉斯哥昏迷评分3分),进行了CT扫描,结果显示蛛网膜下腔出血伴左颞叶血肿,同时伴有严重脑水肿的症状。尽管进行了积极的重症监护,患者仍在八天后死亡。尸检时发现左大脑中动脉动脉瘤破裂。

结论

应激性心肌病不仅可能在严重应激期间发生,也可能在脑出血后心脏骤停复苏后出现。

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