Department of Neurology & Neurosurgery, McGill University, Montreal Neurological Institute, Montreal, Canada.
Neuropsychologia. 2011 Jun;49(7):1816-23. doi: 10.1016/j.neuropsychologia.2011.03.005. Epub 2011 Mar 22.
We provide for the first time direct clinical evidence for the critical role of hemispheric integration in intact error processing. We tested three patients with partial callosal disconnection. Two anterior patients could not correct their errors in a unilateral version of a visuomotor learning task for which they previously exhibited callosal disconnection, whereas, they corrected most of their errors in two visual matching tasks (comparing abstract shapes or faces) that they could transfer between the hemispheres. An opposite pattern emerged in a posterior patient. He could not correct his errors in unilateral versions of the same visual matching tasks, for which he previously exhibited callosal disconnection. However, he corrected most of his errors in the visuomotor learning task he was able to transfer between the hemispheres.
我们首次提供了直接的临床证据，证明了大脑半球整合在完整的错误处理中的关键作用。我们测试了三名胼胝体部分断开的患者。两名前患者无法在单侧视觉运动学习任务中纠正错误，而在可以在两个半球之间转移的两个视觉匹配任务（比较抽象形状或面孔）中，他们纠正了大部分错误。在另一名后患者中出现了相反的模式。他无法在单侧版本的相同视觉匹配任务中纠正错误，而之前他的胼胝体断开。然而，他在可以在两个半球之间转移的视觉运动学习任务中纠正了大部分错误。
