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脓毒症时散在条纹状持续肾显影。

Scattered striated persistent nephrogram in sepsis.

机构信息

Department of Medicine, Hadassah Hebrew University Hospital, Mt. Scopus, Jerusalem, Israel.

出版信息

Nephrol Dial Transplant. 2011 Jun;26(6):2053-5. doi: 10.1093/ndt/gfr113. Epub 2011 Mar 17.

Abstract

Persistent nephrogram, the hallmark of radiocontrast-induced kidney failure, is usually homogenous throughout the kidney and is considered as a generalized shutoff of glomerular filtration, the consequence of altered glomerular hemodynamics, affecting most glomeruli. Herein, we report an incidental finding of scattered persistent nephrogram that was noted in a septic prediabetic hypertensive patient during computerized tomography-guided drainage of a liver abscess. The peculiar patchy striated distribution pattern suggests more centrally altered renal hemodynamics, with hypoperfusion at the level of interlobar and intralobular arteries. Altered renal microcirculation in this case is likely related to the combined effects of prediabetes, sepsis and contrast medium upon renal blood flow regulation, perhaps with consequent focal hypoxic tubular damage.

摘要

持续性肾显影是造影剂诱导肾衰竭的标志,通常在整个肾脏中均匀分布,被认为是肾小球滤过的普遍关闭,是肾小球血流动力学改变的结果,影响大多数肾小球。在此,我们报告了一例偶然发现的散在性持续性肾显影,见于计算机断层扫描引导下肝脓肿引流的糖尿病前期高血压败血症患者。这种特殊的斑片状条纹状分布模式提示更中心的肾血流动力学改变,叶间和小叶内动脉灌注不足。在这种情况下,肾脏微循环的改变可能与糖尿病前期、败血症和对比剂对肾血流调节的综合作用有关,可能导致局灶性缺氧性肾小管损伤。

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