在抑郁症患者中，遵医态度和患者教育对抗抑郁药使用的中介作用。
Mediating roles of adherence attitude and patient education on antidepressant use in patients with depression.
机构信息
Graduate Institute of Clinical Medicine, National Cheng Kung University, Department of Anaesthesiology, Yuli Veterans Hospital, Hualien, Taiwan.
出版信息
Perspect Psychiatr Care. 2011 Jan;47(1):13-22. doi: 10.1111/j.1744-6163.2010.00257.x.
PURPOSE
The purpose of this study was to examine the roles of adherence attitude to antidepressants and patient education as mediators in mediating patients' attitudes toward antidepressant use.
DESIGN AND METHODS
A sample of 201 outpatients, 50 years of age or older, with major depressive disorder, completed a drug use questionnaire, attitudes toward and patient education about antidepressants questionnaire, and Adherence Attitude Inventory.
FINDINGS
Attitudes toward antidepressants were positively associated to antidepressant use, an association explained by the mediating variable, patient education about antidepressants. Adherence attitudes to antidepressants were a mediator that accounted to a significant degree for the causal relationship between attitudes toward antidepressants and antidepressant use.
PRACTICE IMPLICATIONS
Adequate patient education and an understanding of patients' adherence attitude to antidepressant use are needed in nursing practice to reduce patients' uncertainty about treatment and increase successful treatment.
目的
本研究旨在探讨患者对使用抗抑郁药的态度的中介作用中，对抗抑郁药的坚持态度和患者教育的作用。
设计与方法
本研究纳入了 201 名年龄在 50 岁及以上的患有重度抑郁症的门诊患者，他们完成了一份药物使用问卷、对使用抗抑郁药的态度和患者教育问卷以及坚持使用抗抑郁药态度量表。
结果
对使用抗抑郁药的态度与抗抑郁药的使用呈正相关，这种关联可通过患者对使用抗抑郁药的教育来解释。对使用抗抑郁药的坚持态度是一种中介变量，它在很大程度上解释了对使用抗抑郁药的态度和使用抗抑郁药之间的因果关系。
实践意义
在护理实践中，需要进行充分的患者教育，并了解患者对使用抗抑郁药的坚持态度，以减少患者对治疗的不确定性，提高治疗的成功率。
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