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C3b受体在盘状红斑狼疮和系统性红斑狼疮分化中的表达

The expression of C3b receptors in the differentiation of discoid lupus erythematosus and systemic lupus erythematosus.

作者信息

Tausk F, Harpster E, Gigli I

机构信息

Division of Dermatology, University of California, San Diego School of Medicine.

出版信息

Arthritis Rheum. 1990 Jun;33(6):888-92. doi: 10.1002/art.1780330618.

DOI:10.1002/art.1780330618
PMID:2141982
Abstract

We studied the expression of the C3b receptor, CR1, on erythrocytes (E-CR1) of patients who, in spite of having mild systemic symptoms, were diagnosed as having discoid lupus erythematosus and followed accordingly. We found that E-CR1 was markedly reduced in these patients, similar to that seen in patients with systemic disease. In contrast, those patients with completely asymptomatic discoid lupus erythematosus had the same expression of E-CR1 as the normal population.

摘要

我们研究了尽管有轻微全身症状但被诊断为盘状红斑狼疮并接受相应随访的患者红细胞(E-CR1)上C3b受体CR1的表达情况。我们发现这些患者的E-CR1明显降低,与系统性疾病患者的情况相似。相比之下,那些完全无症状的盘状红斑狼疮患者的E-CR1表达与正常人群相同。

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