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管状切开板尿道下裂修复后龟头裂开的危险因素分析。

Analysis of risk factors for glans dehiscence after tubularized incised plate hypospadias repair.

机构信息

Pediatric Urology Section, University of Texas Southwestern Medical Center, Dallas, Texas 75207, USA.

出版信息

J Urol. 2011 May;185(5):1845-9. doi: 10.1016/j.juro.2010.12.070. Epub 2011 Mar 21.

Abstract

PURPOSE

We determined the incidence of glans dehiscence and the associated risk factors after tubularized incised plate hypospadias repair.

MATERIALS AND METHODS

All data for patients undergoing tubularized incised plate hypospadias repair, surgical details and postoperative outcomes were prospectively maintained in databases. Data were analyzed with simple and multiple logistic regression to determine if patient age, preoperative testosterone use, meatal location (distal, mid shaft or proximal), glansplasty sutures (chromic catgut vs polyglactin) or primary vs revision tubularized incised plate procedure was associated with an increased risk of glans dehiscence.

RESULTS

Glans dehiscence occurred in 32 of 641 patients (5%). Age at surgery, preoperative testosterone use and glansplasty suture did not impact the risk of glans dehiscence. Glans dehiscence occurred in 20 of 520 distal (4%), 1 of 47 mid shaft (2%) and 11 of 74 proximal (15%) tubularized incised plate repairs, with the odds of glans dehiscence being 3.6 times higher in patients with proximal vs distal meatal location. Patients undergoing reoperative (9 of 64, 14%) vs primary tubularized incised plate (23 of 577, 4%) had a 4.7-fold increased risk of glans dehiscence.

CONCLUSIONS

Proximal meatal location and revision surgery, most commonly for prior glans dehiscence, increase the odds of glans dehiscence by 3.6 and 4.7-fold, respectively, suggesting anatomical and/or host factors (wound healing) are more important than age, type of suture or preoperative testosterone use in the development of this postoperative complication.

摘要

目的

我们确定了管状切开板尿道下裂修复术后龟头裂开的发生率及其相关危险因素。

材料和方法

所有接受管状切开板尿道下裂修复术的患者的手术细节和术后结果数据均前瞻性地保存在数据库中。我们采用简单和多元逻辑回归分析来确定患者年龄、术前睾酮使用、尿道口位置(远端、中段或近端)、龟头成形术缝线(铬制肠线与聚甘醇酸缝线)或初次与再次管状切开板手术是否与龟头裂开风险增加有关。

结果

641 例患者中有 32 例(5%)发生龟头裂开。手术时的年龄、术前睾酮使用和龟头成形术缝线并不影响龟头裂开的风险。在 520 例远端(4%)、47 例中段(2%)和 74 例近端(15%)管状切开板修复术患者中发生了龟头裂开,近端尿道口位置患者发生龟头裂开的几率是远端患者的 3.6 倍。接受再次手术(64 例中的 9 例,14%)的患者与初次接受管状切开板手术(577 例中的 23 例,4%)的患者相比,龟头裂开的风险增加了 4.7 倍。

结论

近端尿道口位置和再次手术(最常见的原因是先前的龟头裂开)分别使龟头裂开的几率增加 3.6 倍和 4.7 倍,这表明解剖和/或宿主因素(伤口愈合)比年龄、缝线类型或术前睾酮使用在这种术后并发症的发生中更为重要。

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