Lin Yi-Chiao, Wang Wen-Hung, Weng Hsu-Huei, Lin Yen-Chun
Department of Otolaryngology, Chang Gung Memorial Hospital at Chiayi, Taiwan.
Arch Otolaryngol Head Neck Surg. 2011 Mar;137(3):215-9. doi: 10.1001/archoto.2011.10.
To determine the prognostic factors that affect surgical and audiologic outcomes in inlay tympanoplasty after long-term follow-up.
Case series study.
Tertiary referral center.
Sixty-two patients who underwent 71 procedures were enrolled in the study. Patient ages ranged from 31 to 87 years (mean [SD] age, 61.2 [12.9] years). Mean (SD) follow-up was 635.7 (284.7) days. The inclusion criteria were (1) inlay cartilage tympanoplasty performed using local anesthesia via a transcanal route, (2) chronic otitis media with stable perforation, and (3) dry ear without middle ear disease.
The success rate and hearing change at the last follow-up visit.
The overall success rate was 87.3% at the last visit. Using multivariate analysis, sex, age, size of perforation, side of perforation, and the presence of diabetes mellitus and external auditory canal otomycosis did not affect the success. Smoking was the only independent factor for the prognosis of surgical outcome (odds ratio [OR], 8.16; 95% confidence interval [CI], 1.74-36.89; P < .006). On the other hand, age (OR, 6.62; 95% CI, 1.13-38.47; P = .03) and perforation size (OR, 0.11; 95% CI, 0.10-0.79; P = .03) were independent factors for the prognosis of audiologic outcomes.
The frequency of failure was significantly higher for smokers than for nonsmokers. To quit smoking is highly recommended preoperatively for individuals scheduled for chronic otitis media inlay tympanoplasty intervention. Younger patients and those with larger perforations (>50%) were more likely to benefit from this operation.
通过长期随访确定影响嵌体式鼓室成形术手术及听力结果的预后因素。
病例系列研究。
三级转诊中心。
62例患者接受了71次手术,纳入本研究。患者年龄范围为31至87岁(平均[标准差]年龄,61.2[12.9]岁)。平均(标准差)随访时间为635.7(284.7)天。纳入标准为:(1)经耳道途径采用局部麻醉进行嵌体软骨鼓室成形术;(2)慢性中耳炎伴稳定穿孔;(3)中耳无疾病的干耳。
最后一次随访时的成功率及听力变化。
最后一次随访时总体成功率为87.3%。多因素分析显示,性别、年龄、穿孔大小、穿孔侧别、糖尿病及外耳道真菌病的存在均不影响手术成功率。吸烟是手术结果预后的唯一独立因素(比值比[OR],8.16;95%置信区间[CI],1.74 - 36.89;P <.006)。另一方面,年龄(OR,6.62;95% CI,1.13 - 38.47;P =.03)和穿孔大小(OR,0.11;95% CI,0.10 - 0.79;P =.03)是听力结果预后的独立因素。
吸烟者的失败率显著高于非吸烟者。对于计划接受慢性中耳炎嵌体式鼓室成形术干预的患者,强烈建议术前戒烟。年轻患者及穿孔较大(>50%)的患者更可能从该手术中获益。