Response to toremifene (Fc-1157a) therapy in tamoxifen failed patients with breast cancer. Preliminary communication.
作者信息
Ebbs S R, Roberts J, Baum M
机构信息
Department of Surgery, King's College Hospital, London, England.
出版信息
J Steroid Biochem. 1990 Jun 22;36(3):239. doi: 10.1016/0022-4731(90)90016-l.
PMID:2142244
Abstract
Nine patients with measurable lesions of locally advanced or recurrent breast cancer have been treated with toremifene 200 mg daily. A response rate of 33% [complete remission (CR) + partial remission (PR)] or 78% [CR + PR + no change (NC)] has been achieved so far. As all our patients had previously relapsed on anti-oestrogen therapy (tamoxifen), we postulate that our response rate was achieved by a direct oncolytic effect.
摘要
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