Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, Akita 010-8543, Japan.
Clin Exp Nephrol. 2011 Aug;15(4):582-5. doi: 10.1007/s10157-011-0436-y. Epub 2011 Mar 24.
A 22-year-old woman, who often carried heavy books, was admitted for evaluation of hyperreninemic hypertension. Two months prior to admission, she noted leg edema. Radiological examinations revealed bilateral renal infarction with no other abnormal findings. An echocardiography showed a patent foramen ovale (PFO). Hypertension was considered secondary to renal infarction caused by paradoxical embolism through PFO. Antihypertensive and anticoagulant therapy led to improvement of hypertension. In previously reported cases of renal paradoxical embolism, multiorgan involvement was usually observed. Our case is unique in that embolism was confirmed only in the kidneys, and that clinical characteristics of renal embolism were not observed.
一位经常携带重物书籍的 22 岁女性因高肾素性高血压入院接受评估。入院前两个月,她注意到腿部水肿。影像学检查显示双侧肾梗死,无其他异常发现。超声心动图显示卵圆孔未闭(PFO)。高血压被认为是由于 PFO 引起的反常栓塞导致肾梗死引起的。降压和抗凝治疗使高血压得到改善。在之前报道的肾反常栓塞病例中,通常观察到多器官受累。我们的病例独特之处在于仅在肾脏中证实了栓塞,并且未观察到肾栓塞的临床特征。