Department of Hygiene and Public Health, School of Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, 162-8666, Tokyo, Japan,
Environ Health Prev Med. 2002 Jan;6(4):240-7. doi: 10.1007/BF02897976.
The reliability of surveys on smoking habits based on questionnaires was investigated, using the urinary cotinine content as an objective index.
The subjects tested were 2,849 office workers of middle age, who responded to questions concerning their smoking status, and also their urinary cotinine was measured by the HPLC method.
The boundary value between smokers and non-smokers, determined by the histogram independent of the questionnaire, was 63.1 and 79.4 ng/mg of creatinine for males and females, respectively. The rate of misclassification of the non-smokers and former smokers as smokers was 1.3% for males and 1.8% for females, whereas that of current smokers as non-smokers was 6.3% and 2.1%. We also assessed the effect of smoke inhalation on the urinary cotinine value, and found a significant difference for males in the cotinine value by the presence of inhalation and also its depth.
The rate of misclassification in this study was considered to be comparatively low. Several studies have also assessed the reliability of the questionnaire on smoking habits, and found different misclassification rates, indicating the dependence on the race and number of subjects tested. To our knowledge, there were only a few surveys on smoking among large groups, particularly in Japan, such as this one, therefore the results obtained in this study are meaningful.
利用尿中可铁宁含量作为客观指标，调查基于问卷的吸烟习惯调查的可靠性。
检测对象为 2849 名中年办公室工作人员，他们对自己的吸烟状况以及尿中可铁宁含量进行了回答。
根据与问卷无关的直方图确定的吸烟者和非吸烟者的界限值分别为男性 63.1 和女性 79.4ng/mg 肌酐。男性非吸烟者和前吸烟者被错误分类为吸烟者的比例为 1.3%，女性为 1.8%，而女性当前吸烟者被错误分类为非吸烟者的比例为 6.3%，男性为 2.1%。我们还评估了吸烟对尿可铁宁值的影响，发现男性在吸入和吸入深度方面存在明显差异。
本研究的分类错误率被认为相对较低。一些研究也评估了吸烟习惯问卷的可靠性，发现了不同的分类错误率，这表明这取决于种族和测试对象的数量。据我们所知，只有少数大规模的吸烟调查，特别是在日本，有这样的研究，因此本研究的结果是有意义的。
