血链球菌在白塞病发病机制中的作用。
The role of an uncommon type of oral streptococcus sanguis in the etiology of behcet's disease.
机构信息
Major in Health Science, Faculty of Human Sciences, Aichi Mizuho College, 86-1, Haiwa, Hiratobashi-cho, 470-03, Toyota, Japan.
出版信息
Environ Health Prev Med. 1997 Jul;2(2):59-63. doi: 10.1007/BF02931965.
The relationships of Behcet's disease (BD) with oral diseases and the prevalence of an uncommon type of oralStreptococcus sanguis (Str. sanguis) in the oral cavity were investigated in a case-control study. BD patients were compared to patient controls (collagen disease) and healthy controls.An interview questionnaire survey of BD and oral diseases showed that during the pre-onset, onset, and post-onset periods, the incidences of tonsillitis and dental caries, or the history of dental treatment, were greater in BD cases. Typological analysis showed a higher prevalence of an uncommon type ofStr. sanguis, differing from the common type, among BD cases compared to control groups. These results, showing a higher incidence of tonsillitis and dental caries during the presymptomatic period, a greater frequency of dental treatments during the symptomatic period, and the presence of an uncommon type ofStr. sanguis, indicate thatStr. sanguis of an uncommon type is related to increased risk of BD, and the possibility of a causal role is suggested.
在一项病例对照研究中，我们调查了贝切特病（BD）与口腔疾病的关系，以及口腔中一种不常见的血链球菌（Str. sanguis）的流行情况。我们将 BD 患者与患者对照组（胶原病）和健康对照组进行了比较。BD 和口腔疾病的访谈问卷调查显示，在发病前、发病期间和发病后期间，BD 病例中扁桃体炎和龋齿的发生率或牙科治疗史较高。类型分析显示，与对照组相比，BD 病例中一种不常见的血链球菌的流行率更高，与常见类型不同。这些结果表明，在无症状期扁桃体炎和龋齿的发生率较高，在有症状期牙科治疗的频率较高，以及存在一种不常见的血链球菌，表明一种不常见的血链球菌与 BD 的风险增加有关，并提示可能存在因果关系。
Zotero 插件