[元宝枫叶片活性成分的季节变化及其对脂肪酸合酶抑制能力的研究]
[Study on the seasonal variations of the active components in Acer truncatum leaves and the inhibitory ability on fatty acid synthase].
作者信息
Fan Yuan-Jie, Ye Yan-Bin, Gao Wen, Zhang Feng, Zhang Ying-Xia
机构信息
College of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing 100069.
出版信息
Zhong Yao Cai. 2010 Nov;33(11):1740-2.
OBJECTIVE
To study the dynamic variations of the contents of total polyphenols, flvonoids and chlorogenic acid from Acer truncatum leaves in different months, and their inhibitory activities on fatty acid synthase.
METHODS
Spectrophotometry was used to determine the contents of total polyphenols, flavonoids and chlorogenic acid in extracts and the extracts' inhibitory effects were also investigated.
RESULTS
All Leaves picked from May to November have inhibitory effect. But the contents of polyphenols in leaves of July appeared to be higher than other months', and consequently exhibited stronger inhibition against FAS.
CONCLUSION
A positive correlation between the content of polyphenols in leaves extract and the inhibitory efficacy on FAS could be established.
目的
研究不同月份元宝枫叶中总多酚、黄酮类化合物和绿原酸含量的动态变化及其对脂肪酸合酶的抑制活性。
方法
采用分光光度法测定提取物中总多酚、黄酮类化合物和绿原酸的含量，并研究提取物的抑制作用。
结果
5月至11月采摘的叶片均有抑制作用。但7月叶片中多酚含量高于其他月份，因此对脂肪酸合酶的抑制作用更强。
结论
叶片提取物中多酚含量与对脂肪酸合酶的抑制效果之间存在正相关。
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