[Study on formulation of naoxuekang dispersible tablets].

OBJECTIVE

To study the formulation of Naoxuekang dispersible tablets.

METHODS

The formulation was determined by pre-processing leech extractum prior to a series of experiments used to screen excipients like bulking agents and disintegrants and so on, and by adding disintegrants within and without.

RESULTS

Microcrystalline cellulose was determined as the bulking agent, and carboxymethyl cellulose and low-substituted hydroxypropyl cellulose were determined as the disintegrants of Naoxuekang dispersible tablet formula. The average disintegration time and nitrogen content of one tablet were 52 seconds and 5.47 milligrams, respectively. Also disperse homogeneity, weight variation and microbial limit all met the requirements in Ch. P.

CONCLUSION

The prepared Naoxuekang dispersible tablet is reasonable in formula, feasible in technology, which meets the quality standards.