Epidemiol Prev. 2011 Jan-Feb;35(1):18-26.
in recent years, several initiatives have been launched by the Associazione medici diabetologi (AMD) in the context of a national quality improvement program.These activities include: identification of specific indicators of quality of diabetes care, development of a software to calculate such indicators by using routine clinical data, creation of a network of diabetes clinics and analysis and publication of the results in ad hoc reports (AMD Annals). Through the best performer approach, each centre could compare its own performance not only with the theoretical targets suggested by existing guidelines, but also with the results achieved by the best centres operating within the same healthcare system.We evaluated whether the involvement of diabetes clinics into the AMD Annals initiative improved the quality of care over 4 years.
a controlled before and after study was performed to compare data collected from 2004 to 2007 by two groups of centres: group A included centres that had been involved in the project since the first edition of AMD Annals; group B included centres only involved in the last edition.
overall, 124 diabetes clinics provided data on over 100,000 type 2 diabetes patients/year seen from 2004 to 2007.
process indicators included the proportion of patients with at least one measurement of HbA1c, blood pressure and lipid profile during the previous 12 months. Intermediate outcomes included percentages of patients with levels of HbA1c ≤ 7%, blood pressure ≤ 130/85 mmHg and LDL-cholesterol <100 mg/dl (favourable indicators), and the percentages of patients with levels of HbA1c ≥ 9%, blood pressure ≥ 140/90 mmHg and LDL-cholesterol ≥ 130 mg/dl (unfavourable indicators). Percentages of patients treated with insulin, two or more antihypertensive agents, and statins were also evaluated. A multilevel analysis adjusted for age, gender, diabetes duration, and clustering effect was applied to investigate the changes in the indicators between the two groups of centres during 4 years.
lipid profile monitoring increased more in group A (+6.2% from 2004 to 2007) than in group B (+2.4%), while HbA1c and blood pressure monitoring did not change over time in both groups. As for the outcomes considered, the percentage of patients with HbA1c ≤ 7% increased by 6% in group A and by 1.3%in group B, while the proportion of patients achieving the blood pressure target increased in group A (+6.4%), but not in group B (-1.4%). A reduction in the percentage of patients with blood pressure ≥ 140/90 mmHg was found in group A (-7.3%) but not in group B (-0.9%). Marked improvements in the proportion of patients with LDL-cholesterol at target were documented in both groups (group A: +10.5%; group B: +12.2%.) The proportion of patients treated with insulin increased in group A only (+5.8%), while the use of statins grew by 20%in both groups.The proportion of individuals treated with two or more antihypertensive drugs increased by 3.6% in group A and by 1.6% in group B.
the AMD Annals approach can be considered as a case model for quality improvement activities in chronic diseases and a tool to evaluate the level of adoption/acceptance of guidelines in clinical practice. The considerable success documented was obtained without allocation of extra resources or financial incentives but simply through a physician-led effort made possible by the commitment of the specialists involved.
近年来,糖尿病专科医生协会(AMD)在全国质量改进计划的背景下发起了多项倡议。这些活动包括:确定糖尿病护理质量的具体指标,开发一种利用常规临床数据计算这些指标的软件,建立糖尿病诊所网络,并在特设报告(《AMD年报》)中分析和公布结果。通过最佳表现者方法,每个中心不仅可以将自己的表现与现有指南建议的理论目标进行比较,还可以与同一医疗系统内表现最佳的中心所取得的结果进行比较。我们评估了糖尿病诊所在参与《AMD年报》倡议的4年中是否提高了护理质量。
进行了一项前后对照研究,以比较2004年至2007年两组中心收集的数据:A组包括自《AMD年报》第一版起就参与该项目的中心;B组包括仅参与最后一版的中心。
总体而言,124家糖尿病诊所提供了2004年至2007年每年超过100,000名2型糖尿病患者的数据。
过程指标包括在过去12个月内至少进行一次糖化血红蛋白(HbA1c)、血压和血脂检测的患者比例。中间结果包括HbA1c水平≤7%、血压≤130/85 mmHg和低密度脂蛋白胆固醇(LDL - 胆固醇)<100 mg/dl的患者百分比(有利指标),以及HbA1c水平≥9%、血压≥140/90 mmHg和LDL - 胆固醇≥130 mg/dl的患者百分比(不利指标)。还评估了使用胰岛素、两种或更多种抗高血压药物和他汀类药物治疗的患者百分比。应用了一项针对年龄、性别、糖尿病病程和聚类效应进行调整的多层次分析,以研究两组中心在4年期间指标的变化。
A组血脂检测的增加幅度(从2004年到2007年增加6.2%)大于B组(增加2.4%),而两组中HbA1c和血压检测随时间均无变化。至于所考虑的结果,A组中HbA1c≤7%的患者百分比增加了6%,B组增加了1.3%;A组中达到血压目标的患者比例增加(+6.4%),而B组没有增加(-1.4%)。A组中血压≥140/90 mmHg的患者百分比有所下降(-7.3%),而B组没有下降(-0.9%)。两组中LDL - 胆固醇达标的患者比例均有显著改善(A组:+10.5%;B组:+12.2%)。仅A组中使用胰岛素治疗的患者比例增加(+5.8%),而两组中他汀类药物的使用均增长了20%。A组中使用两种或更多种抗高血压药物治疗的个体比例增加了3.6%,B组增加了1.6%。
《AMD年报》方法可被视为慢性病质量改进活动的一个案例模型,以及评估临床实践中指南采用/接受程度的一种工具。所记录的显著成功并非通过分配额外资源或经济激励措施获得,而是仅仅通过参与专家的努力,由医生主导得以实现。